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Weight loss in cats
When to visit the vet?
Non-urgent see a veterinarian within 2–3 days
ORANGE for rapid loss, concurrent inappetence, vomiting/diarrhea, polydipsia/polyuria, or apathy. RED for icterus, respiratory distress, bleeding, or collapse.
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Definition
Weight loss in cats is a condition where a cat unintentionally loses body mass. This can indicate various health problems and should not be ignored, as it is often a symptom of an underlying disease.
Can Occur with the Following Diseases:
- Prostate Adenocarcinoma (Prostate Cancer)
- Thyroid Adenocarcinoma (Thyroid Cancer)
- Acute Liver Insufficiency (Acute Liver Failure)
- Acute Kidney Injury, AKI (Acute Renal Failure)
- Amyloidosis (Protein Deposits in the Body)
- Ancylostomiasis (Parasitic Intestinal Infection with Hookworms, Ancylostoma Species)
- Azotemia, Uremia (High Levels of Nitrogenous Metabolic Products in the Blood)
- Babesiosis (Parasitic Infection Caused by Babesia Species)
- Chemodectoma (Heart and Carotid Artery Tumor)
- Chronic Hypertrophic Pylorus Gastropathy, CHPG (Narrowing of the Gastric Outlet)
- Chronic Hepatitis (Chronic Liver Inflammation)
- Chronic Renal Insufficiency (Chronic Kidney Disease)
- Colitis and Proctitis (Inflammation of the Colon and Rectum)
- Deoxynivalenol Mycotoxicosis, DON (Poisoning with the Fungal Toxin from Fusarium Species, Deoxynivalenol)
- Diabetes Insipidus (Water Diabetes)
- Ehrlichiosis (Bacterial Infection with Ehrlichia Species)
- Exocrine Pancreatic Insufficiency, EPI (Pancreatic Hypofunction)
- Feline Dysautonomia, Key-Gaskell Syndrome (Malfunction of the Autonomic Nervous System)
- Feline Immunodeficiency Syndrome, FIV Infection (Feline AIDS)
- Bile Duct Obstruction
- Biliary Peritonitis (Peritonitis Due to Gallbladder Rupture)
- Gastritis (Inflammation of the Stomach Lining)
- Gastrointestinal infection with Physaloptera species (Parasitic gastrointestinal infection caused by stomach worms, roundworm infection)
- Gastrointestinal Mast Cell Tumors (Mast Cell Tumors in Abdominal Organs)
- Gastrointestinal Motility Disorders (Movement Disorders of the Gastrointestinal Tract)
- Gastroesophageal Reflux (GER) (Acid Reflux)
- Gingival Squamous Cell Carcinoma (Oral Cancer Originating from the Mucous Membrane)
- Gingival Fibrosarcoma (Oral Cancer Originating from the Connective Tissue of the Gums, Gingiva)
- Helicobacteriosis (Bacterial Stomach Infection with Helicobacter Species)
- Hepatic Lipidosis (Fatty Liver)
- Hepatocellular Adenoma, Liver Cell Adenoma (Liver Tumor Originating from the Liver Cells)
- Hepatocellular Carcinoma (Liver Cancer Due to a Carcinoma)
- Heart Tumors in Cats
- Histiocytic Ulcerative Colitis, HCU (Chronic, Ulcerative Inflammation of the Large Intestine, Large Intestinal Ulcer)
- Hypereosinophilic Syndrome (Overproduction of Special White Blood Cells of the Immune System in the Bone Marrow)
- Hyperosmolar Diabetic Coma (Diabetic Coma Due to Hyperglycemia and Dehydration)
- Hypersomatism, Acromegaly (Increased Secretion of the Growth Hormone Somatotropin)
- Hypertension (High Blood Pressure)
- Hypervitaminosis D (Vitamin D overdose toxicity)
- Idiopathic Pulmonary Fibrosis (Hardening of the Lungs)
- Feline Leukemia Virus (FeLV) Infection (Feline Leukemia Virus)
- Infectious Endocarditis (Heart Valve Infection)
- Inflammatory Bowel Disease, IBD (Chronic Inflammatory Bowel Disease)
- Carcinoid Tumors and Carcinoid Syndrome (Carcinoid Cancer)
- Cutaneous Sporotrichosis (Fungal Infection of the Skin with Sporothrix Species)
- Cutaneous and mucocutaneous squamous cell carcinoma (Skin and mucous membrane cancer)
- Laryngeal paralysis
- Leiomyoma (tumor of the stomach, small and/or large intestine originating from the muscle cells)
- Lingual squamous cell carcinoma (tongue cancer)
- Cleft Lip, Jaw, Palate, LCP (Harelip)
- Lyme disease (Bacterial infection caused by Borrelia burgdorferi)
- Lymphoma, Lymphosarcoma (cancer caused by blood cells, the lymphocytes)
- Malignant Fibrous Histiocytoma (Giant Cell Tumor)
- Hemangiosarcoma of the Spleen and/or Liver (Liver and Spleen Cancer Caused by Hemangiosarcoma)
- Mammary Tumor (Milk Gland Tumor)
- Mucocutaneous Plasmacytoma (skin cancer originating from plasma cells, a type of white blood cells)
- Multiple Myeloma (Bone Marrow Cancer)
- Myeloproliferative Disorders (Blood Cancer Disorders)
- Neuroendocrine tumor, Apudoma (intestinal tumor originating from hormone-producing cells)
- Nocardiosis (Bacterial infection with Nocardia)
- Opisthorchis Felineus infection, Opisthorchiasis infection (Parasitic infection with the cat liver fluke)
- Oral Ulcerations (Mouth Ulcers)
- Oral chondrosarcoma (cancer in the oral cavity originating from cartilage tissue)
- Oral squamous cell carcinoma (tumor in the oral cavity originating from the mucous membrane)
- Esophagitis (Inflammation of the Esophagus)
- Esophageal stricture (narrowing of the esophagus)
- Osteosarcoma (Bone Cancer)
- Pancreatic Adenocarcinoma (Pancreatic Cancer)
- Pancreatitis (Inflammation of the Pancreas)
- Panosteitis (Bone and Periosteal Inflammation)
- Paraneoplastic Syndrome (Side effects of cancer)
- Paraneoplastic Skin Syndrome (Skin changes related to cancer)
- Cardiovascular Dirofilariasis (Heartworm Disease)
- Pectus Excavatum (Deformed Sternum, Funnel Chest)
- Perianal Fistula (Chronic Inflammatory Condition of the Anal Region)
- Persistent Right Aortic Arch (Heart Vessel Anomaly)
- Pheochromocytoma (Adrenal Gland Cancer)
- Pulmonary squamous cell carcinoma (lung cancer originating from cells lining the airways)
- Pleural effusion (fluid accumulation in the chest between the parietal and visceral pleura)
- Pneumocystosis (Fungal Infection of the Lung with Pneumocystis Species)
- Polycystic Kidney Disease, PKD (Kidney disease due to cysts)
- Portosystemic shunt, Intrahepatic arteriovenous malformation (Liver shunt)
- Protein-losing enteropathy (protein loss through the intestine)
- Pulmonary Hypertension (High Blood Pressure in the Lungs)
- Pulmonary lymphomatoid granulomatosis (Cancerous lymphatic cells in the lungs)
- Pyruvate Kinase Deficiency, PK (Pyruvate Kinase Deficiency)
- Renal Adenocarcinoma (Kidney Cancer)
- Renomegaly (Kidney Enlargement)
- Rotavirus Gastroenteritis (Intestinal Infection Caused by Rotavirus)
- Sarcocystosis (Parasitic intestinal infection with Sarcocystis species)
- Synovial sarcoma (joint cancer originating from the synovial membrane)
- Systemic Fungal Infection, Systemic Mycosis (Fungal Infection that Affects Various Organs Such as Skin, Nose, Brain, Lungs)
- Toxocariasis (Parasitic Intestinal Infection with Toxocara Species, Roundworm)
- Toxoplasmosis (Parasitic infection with Toxoplasma species)
- Soft Tissue Sarcomas (Tumors of Soft Tissues: Connective, Muscle, or Nerve Tissue)
- Dental Problems
- Cyclic Hematopoiesis (Blood Disorder Related to FeLV Infection)
- Aelurostrongylosis, Aelurostrongylus Abstrusus Infection (Parasitic Lung Infections Caused by Lungworms)
- Bacterial Pneumonia
- Renal anemia (red blood cell deficiency due to chronic kidney disease)
- Arsenic Intoxication (Arsenic Poisoning)
- Feline Chronic Gingivostomatitis, FCGS (Chronic Inflammation of the Gums and Oral Mucosa, Stomatitis)
- Chronic Gastritis (Chronic Stomach Inflammation)
- Intussusception (Intestinal Invagination)
- Adenocarcinoma of the Intestine (Intestinal Cancer Originating from the Glandular Cells)
- Megacolon (Colon Enlargement)
- Feline Small Intestinal Lymphoma (Small Intestinal Cancer in Cats)
- Suppurative Hepatitis and Liver Abscesses
- Myelodysplastic Syndrome, MDS (developmental disorder of blood-forming cells, blood stem cell disease)
- Glaucoma (Elevated Intraocular Pressure)
- Cardiac Hemangiosarcoma (Heart Cancer, Blood Vessel Tumor)
- Ibuprofen Poisoning
- Feline Parvovirus infection, FPV, Feline Panleukopenia (Feline distemper, Panleukopenia)
- Oral Melanoma (cancer of the oral cavity originating from pigment cells, the melanocytes)
- Nasal chondrosarcoma (cancer of the nasal and paranasal sinuses originating from cartilage tissue)
- Gastrointestinal leiomyosarcoma (cancer in the gastrointestinal tract originating from the stomach and intestinal muscle cells)
- Granulomatous Hepatitis (Liver Inflammation with Nodule Formation)
- Chylothorax (Lymphatic Effusion in the Pleural Space in the Chest)
- Eosinophilic Gastroenteritis (Inflammation of the Stomach and Intestines with the Presence of Special White Blood Cells)
- Ulcus ventriculi, Ulcus duodeni (Gastric and duodenal ulcers)
- Stomach worm infection, Ollulanosis (Parasitic infection of the stomach caused by Ollulanus species)
- Squamous cell carcinoma of the tonsils (Tonsil cancer)
- Hypoadrenocorticism (Addison's Disease)
- Hypokalemia (Low Potassium Level in the Blood)
- Glomerulonephritis (Kidney Inflammation)
- Coccidiosis (Parasitic intestinal infection caused by coccidia)
- Trichuriasis (Parasitic intestinal infection caused by whipworms, Trichuris species)
- Leishmaniasis (Parasitic infection caused by Leishmania species)
- Blastomycosis (Fungal Infection Caused by Blastomyces Species)
- Histoplasmosis (Fungal Infection with Histoplasma Species)
- Hyperthyroidism (Overactive Thyroid)
- Lymphadenopathy (Swelling of one or more Lymph Nodes)
- Adenocarcinoma of the Parotid Gland or Mandibular Gland (Salivary Gland Cancer)
- Thymoma (Tumor of the thymus gland)
- Epulis (Tumors of the Gums)
- Esophageal diverticulum (localized pouch in the esophageal wall)
- Splenic Torsion (Twisted Spleen)
- Hypervitaminosis A (Vitamin A overdose poisoning)
- Diabetes Mellitus
- Hiatal Hernia (Diaphragmatic Hernia at the Passage of the Esophagus into the Abdominal Cavity)
- Peritoneopericardial Diaphragmatic Hernia (diaphragmatic hernia with an open connection between the abdominal cavity and the pericardial sac)
- Gastric foreign body (foreign body in the stomach)
- Trichobezoars (Hairballs in the Stomach)
- Feline Spongiform Encephalopathy, FSE (Brain Inflammation Caused by Pathogenic Proteins, Prions)
- Hepatic Coagulopathy (Blood Coagulation Disorder, Liver-Related)
- Pancytopenia (Global Disorder of Blood Formation)
Basics and possible causes
Weight loss in cats can have many causes, ranging from harmless to serious health problems. Basically, weight loss occurs when calorie intake is lower than calorie expenditure. This can be caused by reduced food intake, increased energy requirements, or inefficient nutrient utilization.
A common reason for weight loss is a decreased appetite, also called anorexia, which can be caused by stress, environmental changes, or illness. Diseases affecting the digestive tract, such as gastrointestinal disturbances, can also lead to weight loss, as they impair the cat’s ability to properly absorb and utilize nutrients.
Endocrine diseases such as hyperthyroidism or diabetes mellitus are also known causes. In hyperthyroidism, the thyroid gland produces too many hormones, which accelerates metabolism and leads to increased energy consumption. Diabetes mellitus leads to insufficient insulin levels, which impairs the body’s ability to use glucose and can therefore also cause weight loss.
Furthermore, chronic kidney diseases, liver diseases, or infectious diseases such as FIV (Feline Immunodeficiency Virus) and FeLV (Feline Leukemia Virus) can lead to unintentional weight loss. These diseases affect organ function and the cat’s general health, often leading to reduced food intake and consequently to weight loss.
Typical accompanying symptoms
- Decreased appetite: Cats that eat less or refuse food can quickly lose weight. This can indicate pain or discomfort.
- Vomiting and diarrhea: These symptoms may indicate digestive problems that impair nutrient absorption.
- Increased water intake and urination: These symptoms are typical for diseases such as diabetes mellitus or chronic kidney diseases.
- Behavioral changes: Lethargy, withdrawal, or aggressiveness can indicate a health problem that also causes weight loss.
- Lack of grooming: A cat that grooms less may be suffering from diseases that also lead to weight loss.
When to see a vet?
A vet visit is urgently required if your cat’s weight loss is significant or accompanied by other symptoms. If the cat does not eat for more than a few days or shows visible signs of weakness, quick action should be taken.
Even if the cat shows symptoms such as vomiting, diarrhea, increased drinking, or urination in addition to weight loss, an immediate vet visit is necessary. These symptoms can indicate serious diseases that require prompt treatment.
If the cat is older or already has known health problems, a vet should be consulted for any change in weight. Older cats are more susceptible to diseases that can lead to weight loss and therefore require special attention.
Symptom recognition for the pet owner and veterinary diagnostic procedure
As a pet owner, you can recognize your cat’s weight loss by regularly monitoring your cat’s weight and paying attention to changes in appetite or behavior. If weight loss is noticeable, it is important to have the cat examined by a vet as soon as possible.
The vet will first take a detailed medical history and perform a physical examination. Blood tests can help identify endocrine diseases, kidney or liver problems, and infectious diseases. Urine tests may also be necessary to diagnose diseases such as diabetes or kidney diseases.
Imaging procedures such as X-ray or ultrasound can be used to detect structural abnormalities or tumors that could contribute to weight loss. In some cases, a biopsy may also be necessary to take tissue samples for a more accurate diagnosis.
What the pet owner can do and professional therapy options
As a pet owner, you can take some measures to improve your cat’s condition while waiting for the veterinary diagnosis. Try to minimize stress for your cat by creating a calm and stable environment.
Ensure your cat has access to high-quality and palatable food. Lightly warm the food to intensify the smell, which can stimulate appetite. Offer small, frequent meals to encourage food intake.
Observe your cat’s behavior closely and note any changes you can report to the vet. Ensure your cat has access to fresh water and encourage them to drink to avoid dehydration.
It is important not to administer medication yourself or make drastic changes to the diet without consulting the vet first. The vet will recommend the best course of action based on the specific diagnosis and your cat’s health condition.
Outlook on current research
Weight loss in cats is a symptom that is extensively studied in veterinary medicine, as it is common and can have numerous underlying causes. Researchers focus on understanding the exact mechanisms that lead to weight loss, as well as on developing new diagnosis and treatment approaches. A central research area is the metabolic changes in cats that lose weight despite normal or increased food intake. These studies particularly investigate the role of hormones such as insulin and thyroxine, as well as the effects of age on feline metabolism.
Another focus is on researching intestinal health and the gut microbiota of cats. It is believed that changes in the intestinal flora can significantly contribute to weight loss. Researchers analyze how certain bacterial populations in the gut affect body weight and whether probiotic or prebiotic supplements can help restore balance and thereby stop weight loss.
Additionally, the role of stress and psychological well-being is being investigated. Scientists have found that chronic stress in cats can lead to behavioral changes that affect appetite and thus body weight. Research aims to develop stress-reducing interventions that can minimize weight loss due to behavioral changes.
Future studies are addressing genetics and how genetic predispositions can increase the risk for certain diseases that cause weight loss. Genetic investigations in cats could help identify risk factors and develop personalized treatment approaches.
Finally, there are advances in imaging technologies that enable more accurate diagnosis of underlying problems. Researchers are working to improve ultrasound and MRI techniques to better detect subtle changes in organs and tissues that could be associated with weight loss.