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Definition
Ablatio retinae, also known as retinal detachment, is a serious pathological condition of the eye in which the retina separates from its underlying support layer, the retinal pigment epithelium (RPE). The retina is a light-sensitive tissue layer at the back of the eye responsible for converting light stimuli into electrical signals, which are then transmitted to the brain via the optic nerve. In dogs and cats, retinal detachment is less common than in humans but still represents an ophthalmological emergency requiring immediate veterinary intervention.
Das Wichtigste auf einen Blick
Ablatio retinae, also called retinal detachment, is a serious condition in which the retina detaches from the underlying pigment epithelium, which can lead to vision loss or even blindness. It can be triggered by various causes, including systemic diseases such as hypertension, traumas, inflammatory processes, or hereditary factors.
Symptoms include behavioral changes indicating visual impairment, such as uncertainty when moving, bumping into objects, or altered pupil reactions. Diagnosis is made through ophthalmoscopic examinations, ultrasound, electroretinography, and, if necessary, OCT.
Treatment depends on the cause and includes conservative measures such as therapy for the underlying disease as well as surgical interventions such as vitrectomy and retinopexy. The prognosis depends heavily on the timing of diagnosis and treatment; early intervention yields the best results.
Aftercare includes regular follow-up examinations, continued treatment of underlying diseases, and, if necessary, adjustments to the environment in case of vision loss. Despite the severity of the disease, many animals can achieve a good quality of life with appropriate treatment and care, even if some vision loss remains.
Ursachen
- Trauma or eye injuries
- Severe inflammatory conditions of the eye
- Degenerative changes in the eye
- Elevated intraocular pressure (glaucoma)
- Genetic predisposition in certain breeds
Anatomically, the retina consists of several layers, with the outermost layer containing the photoreceptors (rods and cones). These are responsible for actual light perception. During detachment, the connection between the retina and the pigment epithelium is disrupted, impairing the supply of oxygen and nutrients to the photoreceptors. Without this vital supply, photoreceptors begin to die within hours, which can lead to permanent visual disturbances up to blindness.
The causes of retinal detachment in animals are diverse and can be divided into various categories:
Rhegmatogenous Ablatio Retinae
This form occurs through a tear in the retina, through which fluid from the vitreous space can penetrate into the subretinal space. Triggers can include traumas, degenerative changes of the vitreous body, or spontaneous tears. In older animals, age-related changes of the vitreous body can lead to traction forces that cause retinal tears.
Exudative (serous) ablatio retinae
In this form, fluid accumulates between the retina and pigment epithelium without a tear being present. Inflammatory conditions, vascular changes, or systemic diseases are often the cause. Systemic hypertension, which often accompanies kidney disease, hyperthyroidism, or hyperadrenocorticism, is a significant risk factor. Tumors, abscesses, or vascular disorders can also lead to exudative detachments.
Tractional Ablatio Retinae
This form is caused by traction forces acting on the retina. Fibrovascular membranes or scar tissue forming on the retinal surface can mechanically distort and eventually detach the retina. This often occurs in connection with proliferative retinopathies or severe intraocular inflammatory conditions.
Congenital or Hereditary Factors
Certain dog breeds show a genetic predisposition for retinal diseases that can cause detachments. These include Collie Eye Anomaly (CEA), progressive retinal atrophy (PRA), and other hereditary retinopathies. Particularly susceptible breeds include Collies, Shelties, Labrador Retrievers, Golden Retrievers, and Cavalier King Charles Spaniels.
Systemic Diseases
Various systemic diseases can secondarily lead to retinal detachments. These include hypertension, diabetes mellitus, kidney diseases, hyperthyroidism (especially in cats), hyperadrenocorticism, and various autoimmune diseases. These underlying conditions often lead to changes in blood vessels or inflammatory reactions that can compromise the integrity of the retina.
Symptoms
Symptoms of retinal detachment can vary depending on the extent and location. Since animals cannot directly communicate their vision problems, it is important for pet owners to watch for behavioral changes that could indicate visual impairment.
In cases of partial retinal detachment, affected animals often show subtle signs such as slight uncertainty in unfamiliar surroundings or when climbing stairs. They may also bump into objects more frequently, especially if they are in their peripheral field of vision. Some animals appear more anxious or reserved than usual because they can no longer fully perceive their environment.
In advanced or complete detachments, symptoms become more obvious. Animals may suddenly have difficulty orienting themselves, finding familiar paths, or reacting to movements. They move more cautiously, with their head held high, and may hesitate when jumping down from elevated positions. Increased blinking or heightened sensitivity to light is also frequently observed.
Ophthalmologically, some animals may show dilated pupils (mydriasis) that do not react or only react slowly to light. In secondary inflammation or bleeding, redness, cloudiness, or increased tear production may also occur. In some cases, an abnormal reflex from the inside of the eye is visible when viewed directly with a light source.
It is important to note that retinal detachment is painless in many cases, which is why animals show no obvious signs of discomfort. This can lead to the condition being detected late, worsening the prognosis.
Diagnose
- Fundoscopy to examine the retina
- Ultrasound of the eye to confirm the detachment and assess its extent
- Imaging procedures such as OCT for detailed examination of retinal structure
Ophthalmoscopy (direct and indirect): This is the classic standard procedure for examining the ocular fundus. In cases of detachment, a partially to completely gray-white, bulging area is often visible. In total detachment, the retina may protrude into the vitreous body like a “sail” or “umbrella.”
Ultrasound examination (B-scan sonography): This is the central diagnostic method for opaque optical media (e.g., in cases of cataracts or vitreous bleeding) to indirectly assess retinal detachment. It is useful for evaluating the extent and form (flat, bullous, total detachment) of the retinal detachment.
Electroretinography (ERG): This is used to test retinal function (especially the photoreceptors). In cases of extensive detachment, severely reduced or absent responses are observed. This diagnostic method helps in making prognostic decisions (e.g., whether surgery is advisable).
Optical Coherence Tomography (OCT): This is currently one of the most modern methods for high-resolution imaging of retinal structures. This diagnostic method is increasingly available in specialized veterinary ophthalmology centers. It allows for the precise visualization of defects, subretinal fluid accumulation, and changes in individual retinal layers.
Therapie
- Surgical interventions such as vitrectomy or the introduction of silicone oil or gas to reposition the retina
- Laser therapy or cryotherapy to repair retinal tears and prevent further detachments
- Scleral buckle
- Treatment of the underlying cause of the detachment
Conservative therapy
- Blood pressure control: Blood pressure regulation is essential, especially in cases of exudative and hypertensive retinal detachment. ACE inhibitors, angiotensin II blockers, or other antihypertensive medications can reduce fluid accumulation.
- Therapy for underlying diseases: e.g., kidney disease, hyperthyroidism (very rare in dogs, more common in cats), hyperadrenocorticism.
- Glucocorticoids or other anti-inflammatory medications may be indicated for immune-mediated or inflammatory causes, such as uveitis.
Surgical therapy
- Vitrectomy with retinopexy (laser or cryotherapy) to stabilize the retina.
- Silicone oil or gas tamponade: Keeps the retina stable in attachment to the retinal pigment epithelium (RPE) following the procedure.
- In tractional detachments, connective tissue can be surgically removed to eliminate traction forces.
Prognose und Nachsorge
The prognosis for retinal detachment depends on various factors, including the cause, extent and duration of the detachment, and the speed of treatment. Generally: the earlier the treatment, the better the chances of preserving or restoring visual function.
In cases of exudative detachment caused by systemic diseases such as hypertension, the prognosis is relatively good if the underlying condition can be successfully treated. Many animals regain part of their vision once blood pressure is normalized and the retina reattaches.
For rhegmatogenous or tractional detachments, the prognosis is more guarded. The success of surgical interventions depends heavily on the extent of damage already sustained by the photoreceptors. After about 72 hours without supply, photoreceptors begin to die irreversibly, which limits functional recovery.
Aftercare following treatment is crucial for long-term success. Regular follow-up examinations are necessary to monitor the healing process and detect potential complications early. For surgical procedures involving gas or oil tamponades, specific behavioral rules must be followed to ensure the optimal position of the tamponade.
Medical aftercare often includes anti-inflammatory and antibiotic eye drops, as well as continued treatment of underlying diseases. For animals with permanent vision loss, adapting the environment is important to enable safe orientation.
Long-term, regular monitoring of intraocular pressure and the ocular fundus is important, as animals with retinal detachment may have an increased risk of further eye complications such as glaucoma or recurrent detachments.
Prävention
Prevention of retinal detachment mainly focuses on controlling the underlying diseases that can trigger it. These include hypertension, severe inflammatory conditions, or eye injuries. Regular ophthalmic examinations, especially for genetically predisposed breeds, are crucial. Impacts or traumas to the head should be avoided, and eye injuries should receive immediate veterinary care. For older dogs and animals with systemic diseases, annual blood pressure measurement is recommended. A balanced diet containing antioxidant nutrients can support eye health. Early detection of vision problems is key to preventing irreversible vision loss.
Ausblick auf aktuelle Forschung
Research in the field of veterinary ophthalmology is making continuous progress, which also impacts the diagnosis and treatment of retinal detachments. Current developments focus on several promising areas.
In diagnostics, high-resolution imaging techniques such as spectral optical coherence tomography (SD-OCT) and OCT angiography are increasingly being used. These technologies enable more detailed visualization of retinal structures and retinal perfusion, leading to more precise diagnosis and treatment planning. Artificial intelligence is increasingly being used for automated analysis of these complex image data, which could improve early detection of retinal changes.
In the field of surgical therapy, minimally invasive techniques are being further developed, which place less traumatic stress on the eye and allow for shorter recovery times. New materials for intraocular tamponades with improved properties regarding compatibility and duration of action are being researched. The development of specialized microsurgical instruments for veterinary ophthalmology is also progressing.
A promising field of research is regenerative medicine. Stem cell therapies for the regeneration of damaged retinal cells are still in the experimental phase. Initial studies on laboratory animals show that transplanted retinal progenitor cells can integrate into the retina and establish functional connections. However, the translation of these approaches into clinical veterinary medicine is still pending.
Pharmacological approaches are also being intensively researched. Neuroprotective substances could prolong the survival of photoreceptors after a retinal detachment and thus expand the window for successful treatment. Antiangiogenic factors are being studied for the treatment of proliferative retinopathies that can lead to tractional retinal detachments.
Genetic research is making progress in identifying risk genes for hereditary retinal diseases. This could in the future lead to targeted breeding programs and possibly gene therapeutic approaches to prevent or treat hereditary forms of retinal detachment.
Close collaboration between human and veterinary medicine, in line with the One Health concept, leads to an accelerated transfer of knowledge, from which both sides benefit. Many treatment approaches from human ophthalmology are being adapted and optimized for use in animals.
Frequently Asked Questions (FAQs)
1. What is ablatio retinae (retinal detachment) in dogs?
2. How can I recognize a possible retinal detachment in my dog?
3. What Causes Can Trigger Ablatio Retinae in Dogs?
4. How is retinal detachment diagnosed in dogs?
5. Are there dog breeds that are particularly susceptible to retinal detachment?
6. How is retinal detachment treated in dogs?
7. What is the prognosis for a dog with retinal detachment?
8. Can Ablatio Retinae be Prevented in Dogs?
9. What Aftercare is Important after Treatment or Surgery?
10. Can a Dog with (Partial) Vision Loss Still Lead a Good Life?
Literatur
- Yoshida, G., & Umeda, Y. (2026). Comparison of the incidence of postoperative ocular hypertension after pars plana vitrectomy and phacoemulsification and aspiration in dogs. Journal of the American Veterinary Medical Association. Advance online publication. https://doi.org/10.2460/javma.26.01.0030
- Umeda, Y., Yoshida, G., & Watanabe, N. (2025). Comparison of 27- and 25-gauge pars plana vitrectomy for the treatment of canine rhegmatogenous retinal detachment. Journal of the American Veterinary Medical Association, 263(8), 1–8. https://doi.org/10.2460/javma.24.12.0809
- Lieberman, J. S., Keys, D. A., & Moore, P. A. (2025). Frequency of retinal detachments in dogs after prophylactic transpupillary retinopexy. Veterinary Ophthalmology, 28(6), 910–916. https://doi.org/10.1111/vop.13267
- Beckwith-Cohen, B., & Petersen-Jones, S. M. (2024). Manifestations of systemic disease in the retina and fundus of cats and dogs. Frontiers in Veterinary Science, 11, Article 1337062. https://doi.org/10.3389/fvets.2024.1337062
- Hirashima, S., Takiyama, N., & Umeda, Y. (2022). Outcome of 25-gauge pars plana vitrectomy via a lateral approach without proptosis of the globe: A retrospective study in 72 dogs (78 eyes). Veterinary Ophthalmology, 25(1), 23–30. https://doi.org/10.1111/vop.12912
- Stromberg, S. J., Yan, J., Wisner, T. G., & Good, K. L. (2021). Clinical features and MRI characteristics of retinal detachment in dogs and cats. Veterinary Radiology & Ultrasound, 62(6), 666–673. https://doi.org/10.1111/vru.12999
- Cole, L. P., Jepson, R., Dawson, C., & Humm, K. (2020). Hypertension, retinopathy, and acute kidney injury in dogs: A prospective study. Journal of Veterinary Internal Medicine, 34(5), 1940–1947. https://doi.org/10.1111/jvim.15839
- Acierno, M. J., Brown, S., Coleman, A. E., Jepson, R. E., Papich, M., Stepien, R. L., & Syme, H. M. (2018). ACVIM consensus statement: Guidelines for the identification, evaluation, and management of systemic hypertension in dogs and cats. Journal of Veterinary Internal Medicine, 32(6), 1803–1822. https://doi.org/10.1111/jvim.15331
- Hoffman, A., Sisler, S., Pappania, M., Hsu, K., Ross, M., & Ofri, R. (2018). Electroretinography is a prognostic indicator for postoperative vision in dogs undergoing retinal reattachment surgery. Veterinary Ophthalmology, 21(3), 273–280. https://doi.org/10.1111/vop.12505
- Spatola, R. A., Nadelstein, B., Leber, A. C., & Berdoulay, A. (2015). Preoperative findings and visual outcome associated with retinal reattachment surgery in dogs: 217 cases (275 eyes). Veterinary Ophthalmology, 18(6), 485–496. https://doi.org/10.1111/vop.12246