Fever

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The body temperature of a cat was measured using a digital fever thermometer.

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Guide to fever in dogs and cats

An increase in body temperature above the normal range is referred to as fever. In dogs and cats, this is a body temperature above 40 degrees Celsius (see also normal values for dogs and cats).
Fever and overheating (—> Overheating) are not the same thing.

Fever
Fever is a regulated increase in body temperature by the body in response to inflammation, infection, or immune processes. In dogs, fever is usually spoken of from about 39.2–39.5 °C. High or persistent fever can strain the circulation and organs and should be clarified.

Fever is a natural defense reaction of the body, in which the body temperature rises above the normal range. In dogs and cats, we speak of fever when the body temperature is above 39.5°C. We speak of high fever in our pets from a temperature of 40°C, while critical fever is present from 41°C. The normal temperature in dogs is 37.5–39.0°C, in cats 38.0–39.0°C. However, these values can vary slightly individually and are influenced by factors such as time of day, physical activity, and ambient temperature.

The sudden onset of high fever differs fundamentally from a slow increase in temperature. While a gradual increase gives the body time to adapt, a rapid increase in temperature puts a particular strain on the organism. The rapid change can lead to greater impairments and is often an indicator of acute, potentially life-threatening diseases.

It is important to distinguish between fever and hyperthermia. Fever is caused by a change in the body’s own temperature regulation center in the hypothalamus, usually as a reaction to pathogens or inflammatory processes. Hyperthermia, on the other hand, is overheating due to external factors such as high ambient temperatures or excessive exertion, whereby the temperature regulation center functions normally, but heat dissipation is impaired.

Causes

Fever is usually a sign of an infection. The body’s reaction to raise the body temperature is helpful and should not be combated as a matter of principle. More attention should be paid to the cause of the fever.

  • Bacteria, Parasites, Virus
  • Tumors
  • Autoimmune diseases
  • Chronic inflammatory diseases
  • Hormonal disorders
  • Blockage of a blood vessel (thrombosis)

Attention, in cats, a blockage of a blood vessel in the pelvic area is not uncommon. In these cases, the rectal temperature is not increased, but decreased due to the reduced blood flow.

Sudden high fever in dogs and cats can be triggered by various factors, with infectious causes being the most common. The most important triggers include:

Acute bacterial infections are a common cause of sudden high fever. Septicemia is particularly dangerous, in which bacteria enter the bloodstream and spread throughout the body. This can arise from local infections such as wound infections, abscesses, gingivitis, or urinary tract infections. Leptospirosis, a bacterial zoonosis, can cause sudden high fever in dogs and is transmitted through contaminated water.

Viral infections such as parvovirus or distemper in dogs, as well as feline panleukopenia or feline cold, can also lead to a rapid increase in fever. In cats, FIP (Feline Infectious Peritonitis) and FIV (Feline Immunodeficiency Virus) can be associated with fever. Parasitic diseases such as babesiosis, ehrlichiosis, or anaplasmosis, which are transmitted by ticks, are other possible causes.

Non-infectious causes include immune-mediated diseases such as hemolytic anemias or polyarthritides, which arise from misguided immune responses. Neoplasias (tumor diseases) can also be associated with fever, especially lymphomas and leukemias. Poisoning from toxins such as certain plants, medications, or chemicals can lead to a febrile reaction.

The so-called “Fever of Unknown Origin” (FUO) deserves special attention, in which no clear cause for the fever can be found despite extensive diagnostics. These cases require particularly thorough investigation and monitoring.

In cats, it should be noted that a blockage of a blood vessel in the pelvic area (arterial thromboembolism) can paradoxically lead to a decreased rectal temperature, while the rest of the body has a fever – an important diagnostic clue for veterinarians.

Symptoms

Sudden high fever in dogs and cats

Typical Symptoms:

  • Lethargy, reduced food intake, feeling of warmth
  • Shivering, Panting (not only in heat), increased heart rate
  • In cats, often withdrawal, “painful” behavior

Alarm signs:

  • Very high fever or fever plus apathy/weakness
  • Neurological symptoms (ataxia, Seizures), stiff neck
  • Respiratory distress, pale mucous membranes, petechiae
  • Puppies/kittens, geriatric animals, immunosuppressed patients

Escalation/course:

  • Fever > 24–48 h without recognizable cause → clarification
  • Increasing deterioration within 6–12 h → urgent
  • Fever + dehydration/Vomiting/Diarrhea → escalation due to circulatory risk

 

The clinical picture of an animal with sudden high fever includes characteristic symptoms that are due to the increased metabolism and the immune response. Typical signs include: lethargy, Panting, thirst, Pain, loss of appetite, no water intake, Respiratory distress, Swelling, and sometimes Vomiting.

General impairments are shown by pronounced lethargy and fatigue. The animals appear apathetic, withdraw, and avoid movement. Loss of appetite up to complete food refusal is often observed, while at the same time thirst is often increased. Many animals show an altered posture with a hunched back or drooping head.

The physical signs include hot and dry mucous membranes and an increased respiratory rate. Dogs react with increased Panting, while cats often breathe with their mouths open, which is unusual behavior for them. The heart rate is significantly increased, and warm ears and paws are noticeable during the examination. A change between chills and a feeling of heat is also characteristic, whereby the animals can shiver despite a high body temperature.

In cats, the symptoms may be more subtle than in dogs. They hide more often and show less obvious signs of illness. An important warning sign in cats is the complete loss of grooming.

The severity of the symptoms does not always correlate with the height of the fever. Some animals already show clear impairments at 40 °C, while others hardly show any symptoms at the same temperature. At temperatures above 41 °C, clouding of consciousness, Convulsions, and collapse can occur, as extreme hyperthermia can lead to organ damage.

In addition to these general fever symptoms, other specific signs may occur depending on the underlying disease, such as Cough in respiratory infections, Vomiting and Diarrhea in gastrointestinal diseases, or Lameness in Joint inflammation.

First Aid

  1. Use a digital thermometer. Ear thermometers are often easier to use, but less accurate (Fig.).
  2. Put some Vaseline or oil on a commercially available fever thermometer and insert the thermometer rectally about 2 cm (cat, very small dog) to 5 cm (large dog) and wait until the temperature no longer increases. The rectum runs straight, so you don’t have to worry about damaging the intestine.
  3. Do not let go of the thermometer and remove it if the animal is very restless.
  4. An animal with fever needs rest.
  5. Make sure your animal drinks enough.
  6. You can recognize a lack of fluids, for example, by the fact that less urine is excreted and this looks more concentrated, darker than usual.
  7. Do not use antipyretic drugs without veterinary advice.

Diagnosis

The diagnosis of a sudden high fever begins with the correct temperature measurement. Rectal measurement with a digital thermometer is considered the gold standard. The lightly oiled thermometer is inserted about 2 cm (cat, small dog) to 5 cm (large dog) into the rectum. Alternative measurement methods such as ear thermometers offer more comfort, but provide less precise results.

After the fever has been determined, a systematic diagnosis follows to clarify the cause. The thorough medical history records previous illnesses, vaccination status, medication administration, travel history, and possible exposure risks. During the clinical examination, all organ systems are systematically examined, with particular attention being paid to signs of inflammation, Swelling, and Pain.

The laboratory diagnostic tests form a central component of the diagnosis. The blood count can provide important clues: Leukocytosis indicates bacterial infections, while leukopenia is more likely to occur in viral infections or sepsis. Blood chemistry provides information about organ functions and metabolic disorders. Specific inflammatory marker such as C-reactive protein or serum-Amyloid A can support the diagnosis.

In case of unclear cause, further investigations are indicated. Imaging procedures such as X-ray can provide clues to pneumonia, a foreign body, or tumors. Sonography / ultrasound is suitable for assessing the abdominal organs and for detecting fluid accumulations or abscesses. In complex cases, CT or MRI can provide additional information.

Microbiological examinations include blood cultures in case of suspected bacteremia as well as urine, stool, or tissue samples, depending on the clinical suspicion. PCR tests enable direct pathogen detection in viral or special bacterial infections. Serological tests can detect antibody against specific pathogens.

In case of therapy-resistant fever of unclear origin, more invasive diagnostic measures such as bone marrow biopsy, lymph node biopsy, or an explorative laparotomy may be necessary.

Further veterinary measures

If the symptoms persist for more than a day or additional symptoms such as Drowsiness, Skin changes, Vomiting, Diarrhea, and others occur, do not wait for the fever to disappear on its own, but introduce it to a veterinarian.
Fever is not a disease, but a symptom. Accordingly, the veterinarian will clarify the cause of the fever through a physical examination, laboratory diagnostics, and possibly further procedures such as X-ray, ultrasound, etc.

The treatment of sudden high fever in dogs and cats follows a multi-stage approach that includes both symptomatic therapy and treatment of the underlying cause.

Emergency measures for critical fever (> 41 °C) are initially aimed at lowering body temperature. Controlled passive cooling can be achieved by placing damp cloths on the paws, armpits, and groin. Active cooling measures such as cool (not cold) water baths should be used with caution and only under veterinary supervision, as cooling too quickly can lead to circulatory problems. Fans can support evaporative cooling. The target temperature is about 39 °C, after which cooling should be stopped to avoid hypothermia.

Supportive therapy primarily includes fluid therapy, which is essential for fever patients. Intravenous infusions with isotonic crystalloids compensate for fluid losses and support circulatory function. The infusion rate is individually adjusted to the hydration status and body weight. In severe cases, oxygen therapy may be necessary to support the increased metabolic rate.

Antipyretic (fever-reducing) drugs are used in a targeted manner. Non-steroidal anti-inflammatory drugs such as meloxicam or carprofen may be indicated at temperatures above 40 °C or in cases of severe discomfort. It is important that these drugs are administered only under veterinary supervision, as they can have side effects on the kidneys and gastrointestinal tract. Paracetamol is absolutely contraindicated for cats and can be fatal.

The causal therapy depends on the underlying cause. In bacterial infections, antibiotics are used, initially often as a broad-spectrum antibiotic, later specifically according to an antibiogram. Viral infections usually require symptomatic treatment; antiviral drugs are available for certain pathogens. Parasitic diseases are treated with specific antiparasitics. Immune-mediated diseases often respond to corticosteroids or other immunosuppressants.

In severe cases, intensive care with continuous monitoring of vital parameters may be necessary. Monitoring includes regular temperature checks, ECG monitoring, and blood pressure measurements.

Prognosis and aftercare

The prognosis for sudden high fever depends largely on the underlying disease, the height of the fever, the duration of the condition, and the time of the start of therapy. In general, the earlier the treatment begins, the better the chances of success.

In bacterial infections, the prognosis is usually good if adequate antibiotic therapy is started in time. Viral diseases have different courses – while some, like uncomplicated cat cold infections, have a good prognosis, others, such as parvovirus or FIP, can be more serious. In immune-mediated diseases, the prognosis depends on the response to immunosuppressive therapies.

It becomes critical at temperatures above 41 °C for several hours, as irreversible organ damage is likely. The central nervous system, liver, kidneys, and gastrointestinal tract are particularly at risk. Prolonged hyperthermia can lead to coagulation disorders and, in the worst case, to multiple organ failure.

Aftercare following a Fever episode is crucial for a full recovery. During the convalescence phase, the animal should be kept in a quiet, stress-free environment. Physical exertion should be avoided for at least one week after the Fever subsides to avoid putting additional strain on the organism.

Nutrition plays an important role in the recovery phase. Easily digestible, high-quality food in small, frequent portions supports regeneration. If there is a loss of appetite, feed additives or a special diet can be offered. Adequate hydration remains important even in the aftercare phase.

Check-up examinations are important to monitor the healing process and detect relapses early. Depending on the underlying disease, laboratory tests, imaging procedures, or specific tests may be necessary. The schedule for these follow-up checks is determined individually; typically, the first check takes place after 3–7 days.

Particular attention should be paid to recurring Fever episodes, which may indicate chronic infections, autoimmune diseases, or neoplasms and require further diagnostics.

Summary

Sudden high Fever in dogs and cats is a serious condition that requires quick action. With temperatures above 40 °C, the body reacts to various triggers, with infections being the most common cause. The symptomatology includes lethargy, loss of appetite, increased respiratory and heart rate, as well as warm mucous membranes, and can be supplemented by specific signs depending on the underlying disease.

The diagnosis begins with the correct temperature measurement and includes a systematic clarification through clinical examination, laboratory diagnostics, and imaging procedures. The therapy follows a multi-stage approach with emergency measures to lower the temperature in critical Fever, supportive treatment through fluid therapy and targeted use of antipyretic drugs, as well as causal therapy of the underlying disease.

The prognosis depends largely on the cause, the Fever height, and the time of the start of therapy. Aftercare with adapted housing, special nutrition, and regular check-ups is crucial for complete recovery and to avoid relapses.

Pet owners should know that Fever is not a disease in itself, but a symptom and an important defense reaction of the body. Nevertheless, sudden high Fever requires veterinary attention, as it can indicate serious underlying diseases and, in extreme values, even has organ-damaging effects. Early detection and treatment are the key to successful therapy.

Outlook on current research

Veterinary medicine is continuously developing new approaches to the diagnosis and therapy of febrile diseases in small animals. Current research focuses on several promising areas.

In the field of diagnostics, point-of-care tests are revolutionizing rapid diagnostics. These enable the detection of specific pathogens or inflammatory marker directly in the practice within minutes. New molecular biological methods such as multiplex PCR can test for multiple pathogens in one sample at the same time, which speeds up the diagnosis. The development of specific biomarkers for various Fever causes could enable a more precise differentiation in the future.

In therapy, new antimicrobial substances are being researched that are also effective against multi-resistant pathogens. Targeted immune modulation through specific biologics represents a promising approach for immune-mediated Fever causes. For viral diseases such as FIP in cats, significant progress has been made in recent years with new antiviral substances.

Telemedicine is also gaining importance in veterinary medicine. Remote monitoring systems enable continuous temperature measurement and vital parameter monitoring at home, which can be particularly helpful for chronically ill animals or after Fever episodes. These technologies could enable earlier intervention in the future.

Another research focus is on a better understanding of thermoregulation in different animal species and breeds. Genetic factors that influence the susceptibility to certain febrile diseases are increasingly being identified, which could enable individualized prevention and treatment strategies in the future.

The One Health Initiative, which emphasizes the connection between animal, human, and environmental health, is gaining importance in the research of febrile diseases. Many pathogens that cause Fever in pets have zoonotic potential or are transmitted by vectors whose spread is influenced by climate change.

These research approaches promise improved diagnostics and therapy for febrile diseases in dogs and cats in the coming years, which will ultimately lead to a better prognosis and quality of life for our animal companions.

Frequently asked questions (FAQs)

  1. From what temperature should I take my pet to the vet?
    A visit to the vet is advisable at temperatures above 39.5 °C. Temperatures above 40 °C are an emergency and require immediate veterinary assistance.
  2. Can I give my animal antipyretics myself?
    No, human fever remedies can be dangerous or even fatal for animals. Only administer medication as directed by a veterinarian.
  3. How do I measure the temperature of my pet correctly?
    Rectal measurement with a digital thermometer is the most accurate. Carefully insert the lightly oiled thermometer 2–5 cm (depending on the size of the animal) into the rectum and wait until the measured value is stable.
  4. How can I help my feverish animal at home?
    Offer fresh water, provide a quiet environment, and carefully cool paws and groin with damp cloths if the fever is very high. But always seek veterinary advice.
  5. Can stress trigger fever in my pet?
    Stress alone rarely causes real fever, but can lead to a slight increase in temperature. Persistent temperature increases usually have other causes.
  6. How long does it take for antibiotics to work in a feverish animal?
    As a rule, a decrease in fever should be observed within 24–48 hours after the start of effective antibiotic therapy.
  7. Can my animal die of fever?
    Extremely high fever (over 42 °C) can be life-threatening and lead to organ damage. However, it is not the fever itself, but predominantly the underlying disease that is the real danger.
  8. Why is my cat harder to recognize with fever than my dog?
    As natural prey, cats show symptoms of illness less clearly and often hide when they are unwell, which can make early detection more difficult.
  9. Can I prevent fever?
    Regular vaccinations, parasite prevention, and good hygiene can prevent many fever-causing diseases. Regular veterinary check-ups help to identify problems early.
  10. Is it normal for my animal to develop a slight fever after vaccination?
    A mild increase in temperature (up to about 39.5 °C) can occur in the first 24–48 hours after vaccination and is mostly harmless. Higher or longer-lasting fever should be clarified by a veterinarian.

Literature

  • Goddard, A., & Leisewitz, A. L. (2020). Canine parvovirus. Veterinary Clinics of North America: Small Animal Practice, 50(6), 1307–1327. https://doi.org/10.1016/j.cvsm.2020.08.004
  • Lappin, M. R., Blondeau, J., Boothe, D., Breitschwerdt, E. B., Guardabassi, L., Lloyd, D. H., Papich, M. G., Rankin, S. C., Sykes, J. E., Turnidge, J., & Weese, J. S. (2021). Antimicrobial use guidelines for treatment of respiratory tract disease in dogs and cats: Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases. Journal of Veterinary Internal Medicine, 35(1), 279–294. https://doi.org/10.1111/jvim.15793
  • Löwe, G., & Löwe, O. (2021). Notfälle bei Hund und Katze – Ein tierärztlicher Ratgeber (208 S.). Kynos-Verlag.
  • Neiger, R. (Hrsg.). (2014). Differential diagnoses internal medicine in dog and cat: From the leading symptom to the diagnosis (2nd ed.). Thieme Verlagsgruppe.
  • Pedersen, N. C., Perron, M., Bannasch, M., Montgomery, E., Murakami, E., Liepnieks, M., & Liu, H. (2019). Efficacy and safety of the nucleoside analog GS-441524 for treatment of cats with naturally occurring feline infectious peritonitis. Journal of Feline Medicine and Surgery, 21(4), 271–281. https://doi.org/10.1177/1098612X19825701
  • Ramsey, I. K., & Tasker, S. (2022). Fever. In S. J. Ettinger, E. C. Feldman, & E. Côté (Hrsg.), Textbook of veterinary internal medicine (8. Aufl., S. 142–146). Elsevier.
  • Sykes, J. E. (2023). Canine and feline infectious diseases (2nd ed.). Elsevier Saunders.