Epistaxis (Nosebleed)

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Bleeding in dogs or cats

Nose bleeds (epistaxis)
Epistaxis (nosebleed) is bleeding from the nasal cavity, unilateral or bilateral, that can occur spontaneously or after trauma. Possible causes include foreign bodies, inflammatory conditions, tumors, blood coagulation disorders or high blood pressure. Severe or recurrent nose bleeds (epistaxis) requires timely diagnostics.

Nose bleeds (epistaxis) is the escape of blood from the nostrils or the nasal cavity. Unlike in humans, nose bleeds (epistaxis) in dogs and cats is a rarer, but usually more serious symptom. The anatomical peculiarity of the nasal cavity in pets requires a rich blood supply through numerous vessels, which can lead to sometimes considerable bleeding in the event of injuries or diseases. The nasal mucosa is particularly sensitive and well supplied with blood, which makes it susceptible to bleeding. In dogs and cats, the nose bleeds (epistaxis) can occur unilaterally or bilaterally and varies in its intensity from slight oozing to massive, life-threatening bleeding. The bleeding can originate from the anterior nasal area (anterior epistaxis (nosebleed)) or from the posterior nasal cavity (posterior epistaxis (nosebleed)), the latter often being more serious as blood can flow into the pharyngeal cavity and lead to respiratory distress.

Causes

The causes of nose bleeds (epistaxis) in pets are varied and can be divided into local and systemic factors. Local causes include foreign bodies in the nose, which can be picked up by sniffing, such as blades of grass, small twigs or seeds. Traumatic injuries from falls, accidents or fights with other animals can also cause nose bleeds (epistaxis). Inflammatory conditions of the nasal mucosa (rhinitis) or the paranasal sinuses (sinusitis) are other common local causes.

In dogs, fungal infections, especially aspergillosis, are an important cause of chronic nose bleeds (epistaxis). This infection mainly affects long-nosed breeds and can cause considerable damage to the nasal mucosa. In cats, on the other hand, infections with the pathogen Cryptococcus neoformans are more common.

Tumors in the nasal and pharyngeal cavity are among the more serious causes and occur particularly in older animals. In dogs, approximately 80% of nasal tumors are malignant, while in cats, lymphomas are more common.

Systemic causes include blood coagulation disorders, which can be congenital (such as Von Willebrand’s disease in certain dog breeds) or acquired (due to poisoning with anticoagulant substances such as rat poison). Liver diseases can also lead to blood coagulation disorders, as the liver is responsible for the production of coagulation factors. High blood pressure, especially in older cats with kidney disease, can also cause nose bleeds (epistaxis).

Breed-specific predispositions play a role: Brachycephalic (short-headed) breeds such as pugs or bulldogs are more prone to anatomical abnormalities that can lead to nose bleeds (epistaxis), while certain collie breeds may have genetically determined blood coagulation disorders.

Symptoms

Nose bleeds (epistaxis) in dogs and cats

Typical Symptoms:

  • Unilateral or bilateral nose bleeds (epistaxis), sneezing, licking
  • Bloody drops/traces, possibly nose rubbing
  • In mild form: short-term, self-limiting

Alarm signs:

  • Severe or recurrent bleeding, blood runs into the throat (cough/gagging)
  • Bilateral epistaxis (nosebleed), bloody mucous membranes/petechiae
  • Weakness, pale mucous membranes, respiratory distress
  • Trauma to the head, suspicion of foreign body/tumor (unilateral + foul odor)

Escalation/course:

  • Recurring over days/weeks → clarification of blood coagulation, blood pressure, tumor/infection
  • Increasing amount of blood within hours → emergency
  • Epistaxis (nosebleed) + hematomas/petechiae → high-grade blood coagulation emergency

The most obvious symptom is blood coming out of one or both nostrils. The bleeding can be dripping, trickling or spraying, depending on the severity and origin of the bleeding. Accompanying symptoms may include sneezing, nasal discharge or rubbing the nose on objects. In the case of heavier bleeding or if blood flows into the throat, gagging, coughing or swallowing of the blood may occur, which can lead to bloody vomiting.

Animals with nose bleeds (epistaxis) often show behavioral changes such as restlessness, anxiety or lethargy. In the event of massive blood loss, signs of shock may occur: pale mucous membranes, increased heart rate, shallow breathing and weakness leading to collapse. Chronic nose bleeds (epistaxis) can lead to anemia, recognizable by lethargy, reduced performance and pale mucous membranes.

In the case of nasal tumors or chronic inflammatory conditions, additional symptoms such as unilateral facial swelling, deformation of the bridge of the nose, eye discharge or neurological symptoms due to pressure on the brain may occur. Respiratory distress is a particularly alarming symptom that requires immediate veterinary attention.

First Aid

  1. Keep your pet calm.
  2. Do not raise the head. The aim is not for the blood to run backwards into the throat.
  3. Manipulations such as cooling are often unfavorable due to the animal’s distress.

Diagnosis

The diagnosis of nose bleeds (epistaxis) requires a systematic approach. First, the veterinarian performs a thorough medical history, in which information about the onset, duration and frequency of the bleeding as well as possible triggers or accompanying symptoms are requested. The clinical examination includes the assessment of vital signs, mucous membrane color and capillary refill time (CRT) to assess the circulatory status.

Laboratory tests are crucial to identify systemic causes. A complete blood count can provide information on inflammatory conditions, infection or anemia. Blood coagulation parameters such as platelet count, prothrombin time (PT) and activated partial thromboplastin time (aPTT) help to assess blood coagulation. Liver and kidney values can indicate organ diseases that cause blood coagulation disorders or high blood pressure.

Imaging procedures play a central role in diagnostics. X-rays of the skull can provide information on fractures, foreign bodies or pronounced changes. Computed tomography (CT) and magnetic resonance imaging (MRI) enable a detailed representation of the nasal and paranasal sinuses and are particularly valuable in the diagnosis of tumors, inflammatory conditions or deeper foreign bodies.

Rhinoscopy, an endoscopic examination of the nasal cavity, allows direct visualization of the nasal mucosa and can be used to take tissue samples or remove foreign bodies. Biopsies are often necessary to diagnose tumors and determine their type. If a fungal infection is suspected, specific cultures are created or PCR tests are performed.

Blood pressure measurement plays an important role, especially in cats, as high blood pressure is a common cause of nose bleeds (epistaxis) in this species.

Further veterinary measures

The treatment of nose bleeds (epistaxis) depends on the underlying cause and the severity of the bleeding. In acute nose bleeds (epistaxis), the initial focus is on stabilizing the patient. This includes rest, slight cooling of the nasal region and a slightly lowered head position to facilitate drainage of the blood and avoid swallowing. In the case of severe bleeding, inpatient admission with intravenous fluid therapy and, if necessary, blood transfusions may be necessary.

Local causes require specific treatments: Foreign objects are removed under sedation or anesthesia, with rhinoscopy often being helpful. Antibiotics are used for bacterial infections, and their selection is ideally based on an antibiogram. Fungal infections such as aspergillosis require long-term antifungal therapy, which can be systemic or local through irrigation of the nasal cavity.

Tumors pose a particular challenge. Therapy options include surgical removal, radiation therapy and, in some cases, chemotherapy. The choice depends on the type of tumor, its location and the general condition of the animal. In the case of inoperable tumors, palliative radiation therapy can help to improve the quality of life.

In systemic causes such as blood coagulation disorders, treatment of the underlying disease is crucial. In the case of poisoning with anticoagulants, vitamin K is administered as an antidote. Liver diseases require comprehensive therapy that includes medication, diet and supportive measures. High blood pressure is treated with antihypertensive drugs such as ACE inhibitors.

In severe cases, hemostatic drugs such as tranexamic acid or etamsylate can be used. In the case of therapy-resistant bleeding, a tamponade of the nasal cavity or, in rare cases, a surgical procedure to ligate bleeding vessels may be necessary.

Prognosis and aftercare

The prognosis for nose bleeds (epistaxis) varies greatly depending on the underlying cause. In the case of one-off bleeding caused by trauma or foreign bodies, the prognosis is usually good after successful treatment. Bacterial infections usually respond well to antibiotics, while fungal infections require a longer treatment period and relapses are possible.

In the case of tumors, the prognosis depends on the type of tumor, the stage at diagnosis and the available treatment options. Unfortunately, many nasal tumors in dogs and cats have a cautious to unfavorable prognosis, as they are often only detected in advanced stages.

Systemic diseases such as blood coagulation disorders or high blood pressure require continuous monitoring and treatment, with the prognosis depending on the controllability of the underlying disease.

Aftercare includes regular check-ups with the veterinarian, monitoring for recurrence of bleeding and consistent implementation of the prescribed therapy. In the case of chronic underlying diseases, regular blood tests and, if necessary, imaging procedures are important for monitoring the course of the disease.

Pet owners should pay attention to signs of relapse and know how to react in an emergency. A calm environment for the animal, avoidance of physical exertion and stress, and an adapted diet can support recovery.

Summary

Nose bleeds (epistaxis) in dogs and cats is a serious symptom that can have various causes, from harmless foreign bodies to serious systemic diseases or tumors. Unlike in humans, nose bleeds (epistaxis) is rarer in pets and should therefore always be clarified by a veterinarian.

The diagnosis requires a thorough examination, which includes laboratory tests, imaging procedures and, if necessary, endoscopic examinations. The treatment depends on the underlying cause and ranges from simple measures such as the removal of foreign bodies to complex therapies for tumors or systemic diseases.

The prognosis depends heavily on the cause, with local, treatable problems having a better prognosis than advanced tumors or severe systemic diseases. Consistent aftercare and observation of the animal for signs of relapse are important for long-term treatment success.

Pet owners should know how to provide first aid in the event of acute nose bleeds (epistaxis) and when a visit to the veterinarian is urgently required. A calm approach to the animal and the avoidance of stress can help to avoid worsening the nose bleeds (epistaxis).

Outlook on current research

Research in the field of diagnostics and treatment of nose bleeds (epistaxis) in pets is constantly evolving. New imaging techniques with higher resolution enable a more precise representation of the nasal cavities and adjacent structures, leading to earlier and more accurate diagnosis. The development of minimally invasive endoscopic techniques improves the possibilities for taking tissue samples and treating diseases in the nasal cavity with less stress for the animal.

In the field of tumor treatment, targeted therapies are being researched that are specifically tailored to the molecular properties of certain tumors. Immunotherapeutic approaches that activate the body’s own immune system to fight tumors are showing promising results in preclinical studies.

The improvement of diagnostic tests for fungal infections enables a faster and more reliable diagnosis of this common cause of nose bleeds (epistaxis) in dogs. New antifungal agents with better efficacy and fewer side effects are under development.

Advances in blood coagulation research are leading to a better understanding of rare blood coagulation disorders and the development of more specific treatment options. The increasing availability of point-of-care coagulation tests (blood coagulation tests at the site of the event) enables faster diagnosis and initiation of therapy in emergency situations.

Frequently asked questions (FAQs)

  1. Is nose bleeds (epistaxis) in my pet always an emergency?
    Not every nose bleeds (epistaxis) requires immediate veterinary attention, but it should never be ignored. Immediate help is necessary in the event of severe or persistent bleeding, respiratory distress, weakness or if the animal is already suffering from known diseases.
  2. Can I help my dog or cat myself with nose bleeds (epistaxis)?
    You can provide first aid by calming your animal, keeping its head slightly down and cooling it gently if necessary. Avoid manipulating the nose and take the animal to the vet if the bleeding persists.
  3. Why is my animal only bleeding from one nostril?
    Unilateral nose bleeds (epistaxis) often indicates a local cause such as a foreign body, unilateral inflammatory conditions or a tumor. It is important to have this clarified by a veterinarian.
  4. Can certain dog breeds suffer from nose bleeds (epistaxis) more often?
    Yes, brachycephalic breeds such as pugs or bulldogs are more susceptible to nasal problems due to their anatomy. Certain collie breeds may have genetically determined blood coagulation disorders that can lead to nose bleeds (epistaxis).
  5. How can I tell if my cat has high blood pressure?
    High blood pressure does not cause specific symptoms, but can lead to nose bleeds (epistaxis), eye changes or neurological symptoms. A blood pressure measurement by the veterinarian is required for diagnosis.
  6. Are nasal tumors in pets always malignant?
    In dogs, approximately 80% of nasal tumors are malignant, while the ratio is somewhat more favorable in cats. A biopsy is necessary for accurate determination.
  7. How long does the treatment of a fungal infection in the nose take?
    The treatment of fungal infections such as aspergillosis can take several months and requires regular check-ups. The exact duration depends on the severity of the infection and the response to therapy.
  8. Can stress trigger nose bleeds (epistaxis) in my pet?
    Stress alone rarely causes nose bleeds (epistaxis), but can lead to a deterioration in animals with high blood pressure or existing nasal problems.
  9. Which poisonings can lead to nose bleeds (epistaxis)?
    In particular, rodenticides (rat poison) with an anticoagulant effect can lead to nose bleeds (epistaxis) and other bleeding. Certain plants and medications can also cause bleeding in rare cases.
  10. Can a special diet prevent or treat nose bleeds (epistaxis)?
    A balanced diet supports general health, but there is no specific diet for nose bleeds (epistaxis). In the case of blood coagulation disorders, a vitamin K-rich diet can have a supportive effect, but should always be discussed with the veterinarian.

Literature

  • Lent, S. E., & Hawkins, E. C. (1992). Evaluation of rhinoscopy and rhinoscopy-assisted mucosal biopsy in diagnosis of nasal disease in dogs: 119 cases (1985–1989). Journal of the American Veterinary Medical Association, 201(9), 1425–1429. https://doi.org/10.2460/javma.1992.201.09.1425
  • Lobetti, R. G. (2009). A retrospective study of chronic nasal disease in 75 dogs. Journal of the South African Veterinary Association, 80(4), 224–228. https://doi.org/10.4102/jsava.v80i4.212
  • Löwe, G., & Löwe, O. (2021). Notfälle bei Hund und Katze – Ein tierärztlicher Ratgeber. Kynos-Verlag.
  • Meler, E., Dunn, M., & Lecuyer, M. (2008). A retrospective study of canine persistent nasal disease: 80 cases (1998–2003). Canadian Veterinary Journal, 49(1), 71–76. (DOI nicht verfügbar)
  • Müller, S. (2017). Memorix Notfallmedizin (10. Aufl.). Georg Thieme Verlag.
  • Plickert, H. D., Tichy, A., & Hirt, R. A. (2014). Characteristics of canine nasal discharge related to intranasal diseases: A retrospective study of 105 cases. Journal of Small Animal Practice, 55(3), 145–152. https://doi.org/10.1111/jsap.12175
  • Reed, N., & Gunn-Moore, D. (2012). Nasopharyngeal disease in cats: Diagnostic investigation and management. Journal of Feline Medicine and Surgery, 14(5), 306–315. https://doi.org/10.1177/1098612X12444997