News on the diagnosis and therapy of cancer in dogs
A communication from the biotechnology company Calviri, published in June 2024, indicates that the research and development of new diagnostic, preventive, and therapeutic approaches against cancer in dogs is rapidly advancing. The following areas are of particular focus:
Diagnostic multi-cancer blood test:
Highly sensitive testing methods with novel biomarkers will soon make it possible to detect a large number of different types of Tumors in very early stages using a simple blood sample. This early detection promises a significantly improved prognosis, as therapy options are more effective the earlier a Tumor is discovered.
Therapeutic vaccines against Tumors in early stage (stage 1):
In direct connection with the diagnostic multi-cancer test, therapeutic vaccines are being developed that aim to specifically combat even the smallest accumulations of cancer cells. This can prevent or at least slow down the spread of Tumors. Such vaccines can also be useful after surgical Tumor resections to detect and effectively combat remaining residual Tumor cells.
Prophylactic vaccination against numerous types of Tumors:
A vaccination strategy is also under development that prevents the development of various types of Tumors from the outset. Such a prophylactic vaccination teaches the immune system to recognize emerging Tumor cells as foreign and to eliminate them early, even before a clinically relevant Tumor develops.
Specialized test for the five most common types of Tumors in the early stages:
Another project aims to establish a test that can specifically detect the five most common types of Tumors in the early stages in dogs. Such precise diagnostics not only facilitates the selection of appropriate therapies but also improves the long-term prospects for affected animals.
Therapeutic vaccine against hemangiosarcoma:
Hemangiosarcoma is known for its particular Aggressiveness. The development of a specialized vaccine, used alone or in combination with surgical and other forms of therapy, could significantly improve the chances of survival and the quality of life of affected dogs.
According to a report by the News service Biospace on October 1, 2024, a dog was vaccinated against hemangiosarcoma for the first time on September 30, 2024, as part of a test series. Leading veterinary oncology facilities at the University of Wisconsin, Colorado State University, and the University of California-Davis are involved in this study.
These research priorities give hope that prevention, early detection, and targeted, effective therapy of Tumors in the early stages will soon be possible in dogs.
