{"id":36052,"date":"2024-06-05T12:28:36","date_gmt":"2024-06-05T10:28:36","guid":{"rendered":"https:\/\/petsvetcheck.de\/krankheiten-und-stoerungen\/hund\/atrioventrikulaere-klappenendokardiose-chronische-herzklappenentzuendung\/"},"modified":"2026-10-15T14:56:03","modified_gmt":"2026-10-15T12:56:03","slug":"atrioventricular-valve-endocardiosis-chronic-heart-valve-inflammation","status":"publish","type":"krankheit","link":"https:\/\/petsvetcheck.de\/en\/diseases-and-disorders\/dog\/atrioventricular-valve-endocardiosis-chronic-heart-valve-inflammation\/","title":{"rendered":"Leaky Heart Valves in Dogs (Myxomatous Atrioventricular Valve Degeneration, Endocardiosis)"},"content":{"rendered":"","protected":false},"featured_media":0,"template":"","krankheitsort":[140],"haufigkeit":[134],"organsystem_krankheiten":[226],"class_list":["post-36052","krankheit","type-krankheit","status-publish","hentry","krankheitsort-brustkorb-en","haufigkeit-a-en","organsystem_krankheiten-cardiovascular-system","entry"],"acf":{"synonyme":"Atrioventricular valve endocardiosis","synonyme_en":"Chronic degenerative valve disease (CDVD), Mitral valve disease","titel_en":"Atrioventricular valve endocardiosis","weitere_suchbegriffe":"","triage":"yellow","triage_begruendung":"Common heart valve disease; timely treatment prevents pulmonary congestion.","definition":"Atrioventricular valve endocardiosis, also known as chronic valvular heart disease, is a common heart condition in dogs characterized by degenerative changes in the heart valves, particularly the mitral valve. This condition leads to an insufficient closing function of the valves, which can result in heart murmurs and potential heart failure. ","ursachen":"The heart valves play a crucial role in regulating blood flow in the heart by ensuring that blood flows in the correct direction. In atrioventricular valve endocardiosis, the valves thicken and deform, primarily affecting the mitral valve, but it can also affect the tricuspid valve. These structural changes lead to a backflow of blood into the atria, which is called regurgitation.  \n\nThe exact causes of these degenerative changes are not yet fully understood, but genetic factors are believed to play a significant role. Certain dog breeds, such as Cavalier King Charles Spaniels, Poodles, Chihuahuas, and Dachshunds, show a higher predisposition to this condition. Age is also a significant risk factor, as the likelihood of developing the disease increases in older dogs.  \n\nThere is also evidence that hormonal and metabolic factors associated with the aging process can contribute to the development of the disease. Furthermore, environmental influences and dietary habits may play a role, although this has not yet been conclusively researched. ","auswahl_symptome_rot":[33880,33807,33869,33261],"auswahl_symptome_blau":[34034,34314,34024,33803],"auswahl_symptome_grun":[33489,33182,33786],"erganzungen_zu_symptomen":"The symptoms of atrioventricular valve endocardiosis can vary depending on the severity of the disease. In the early stages, dogs may be asymptomatic or show only mild clinical signs. A typical first sign is the appearance of a heart murmur, detected by the veterinarian during a routine examination.  \n\nAs the disease progresses, affected dogs often develop symptoms such as cough, which occurs especially at night or during exertion, respiratory distress, reduced resilience, and lethargy. These symptoms are due to the backflow caused by inadequate blood flow. \n\nIn advanced cases, Heart failure can occur, manifesting as severe Respiratory distress, abdominal swelling due to fluid accumulation (ascites), and Weight gain due to fluid retention. Some dogs may also experience fainting spells or weakness. ","zusammenfassung":"Atrioventricular valve endocardiosis is a heart disease in dogs where the heart valves thicken and deform, primarily affecting the mitral valve. These changes lead to a backflow of blood into the atria and impair blood flow. The exact causes are unclear, but genetic factors and age play a role. Certain breeds like Cavalier King Charles Spaniels and Poodles are more commonly affected. Symptoms include reduced exercise tolerance, Respiratory distress, and Cough. The diagnosis is made through clinical examination, heart ultrasound, and possibly X-rays. Therapy aims to alleviate symptoms and slow the progression of the disease, often through medication and lifestyle changes. In severe cases, heart valve surgery may be considered, but it is complex and risky. The prognosis depends on the stage of the disease and the response to therapy. Early diagnosis and regular veterinary monitoring are crucial. Prevention is difficult, but responsible breeding practices and a healthy lifestyle can reduce the risk. Research focuses on genetic factors, new diagnostic techniques, and treatment approaches to improve the quality of life for affected dogs.           ","diagnose":"The diagnosis of atrioventricular valve endocardiosis usually begins with a thorough clinical examination by a veterinarian. A heart murmur heard with a stethoscope is often the first indication of the disease. However, further examinations are necessary to accurately determine the extent of the heart valve disease.  \n\nAn echocardiogram (heart ultrasound) is the best method to assess the structure and function of the heart valves. This imaging technique allows the veterinarian to visualize valve movements, measure valve thickness, and evaluate the extent of regurgitation. Chest X-rays can also be helpful in detecting an enlarged heart and fluid accumulation in the lungs.  \n\nAdditionally, electrocardiograms (ECGs) may be performed to identify Cardiac arrhythmia, which often occur in advanced heart valve disease. In some cases, a blood test may also be performed to rule out other possible causes for the symptoms and to assess the dog's general health. ","behandlung":"The therapy for atrioventricular valve endocardiosis aims to alleviate symptoms, slow the progression of the disease, and improve the affected dog's quality of life. In the early stages of the disease, regular monitoring and lifestyle adjustments may be sufficient. These include a balanced diet, controlled exercise, and avoiding stressful situations.  \n\nMedically, diuretics can be used to reduce fluid accumulation in the body, and ACE inhibitors to control blood pressure and slow the progression of heart disease. In some cases, medications to control Cardiac arrhythmia may also be necessary. It is important that the medication is individually tailored to the dog and regularly reviewed by the veterinarian.  \n\nIn severe cases, surgical intervention may be considered, especially if medical therapy is no longer effective. However, heart valve surgery is complex and is only performed in specialized veterinary clinics. This option is generally more expensive and carries its own risks.  ","prognose":"The prognosis for dogs with atrioventricular valve endocardiosis depends on several factors, including the extent of valve damage, the presence of symptoms, and the response to therapy. In the early stages of the disease, when there are few or no symptoms, dogs can often lead a relatively normal life with regular veterinary monitoring and appropriate care. \n\nIn more advanced cases, however, the disease can lead to chronic heart failure, which significantly impairs the quality of life and shortens life expectancy. Timely diagnosis and individualized therapy can help slow the progression of the disease and extend life. ","ausblick_auf_aktuelle_forschung":"Research into Atrioventricular Valve Endocardiosis (Chronic Degenerative Valve Disease, CDVD) in dogs focuses on several key areas. Researchers are investigating the genetic factors that influence susceptibility to this disease. It is suspected that certain dog breeds have a genetic predisposition to developing this disease, which underscores the importance of genetic studies.  \n\nAnother important research area is the improvement of diagnostic methods. Current standard methods include physical examinations and imaging techniques such as ultrasound. Researchers are working on developing new biomarkers and non-invasive tests that could enable earlier and more accurate diagnosis. Such advances could significantly improve the prognosis for affected dogs.   \n\nIn therapeutic research, the focus is on developing new drugs and treatments that could slow down or even stop the progression of the disease. Current treatment options focus primarily on controlling symptoms and improving quality of life. New approaches, including the use of stem cells and gene therapy techniques, are also being investigated.  \n\nAnother exciting area of research is the investigation of environmental factors that could contribute to the development of CDVD. Dietary habits, physical activity, and other lifestyle factors are being investigated for their influence on the development and course of the disease. This research could lead to preventive measures that reduce the risk of CDVD in dogs.  \n\nIn addition, intensive work is being done to improve surgical techniques. Surgical interventions to repair or replace affected heart valves are complicated and risky. New minimally invasive techniques and improved postoperative care protocols could increase the success rates of such operations and shorten recovery time.  \n\nInternational collaborations play a crucial role in these research efforts. By sharing data and collaborating in large clinical trials, researchers can gain new insights more quickly and develop more effective treatment strategies. These global efforts are essential to improve the understanding and treatment of this widespread disease.  \n\nOverall, research on Atrioventricular Valve Endocardiosis has made significant progress in recent years. However, much remains to be done to fully understand the complex mechanisms of this disease and to develop more effective treatment options. However, ongoing research offers hope that future generations of dogs can be better protected from the effects of this disease.  ","zusatzlicher_inhalt_im_hauptteil":"Since genetic factors play a significant role in the development of atrioventricular valve endocardiosis, prevention of the disease is challenging. In dogs from breeds predisposed to the disease, responsible breeding practices can help minimize the risk. This includes the selection of breeding animals that show no signs of the disease.  \n\nRegular veterinary examinations are crucial to detect and treat the disease early. A healthy diet and a balanced exercise program can also help promote overall heart health and reduce the risk of heart problems. \n\nAlthough complete prevention of the disease is not possible, a combination of genetic selection, regular monitoring, and a healthy lifestyle can significantly reduce the impact of atrioventricular valve endocardiosis on a dog's life.","haufig_gestellte_fragen_faqs":"<b>What is Atrioventricular Valve Endocardiosis?<\/b>  Atrioventricular valve endocardiosis is a chronic heart valve disease common in dogs. It leads to thickening and degeneration of the heart valves, which impairs heart function. \n\n<b>What symptoms does a dog with this disease show?<\/b> Common symptoms include cough, respiratory distress, lethargy, loss of appetite, and, in advanced stages, fainting spells or sudden weakness.\n\n<b>Can all dog breeds be affected by this disease?<\/b> Yes, in principle all dog breeds can be affected, but small breeds such as Cavalier King Charles Spaniels, Poodles, and Dachshunds are more commonly affected.\n\n<b>How is the disease diagnosed?<\/b>  The diagnosis is usually made through a combination of physical examination, X-rays, heart ultrasound examinations, and blood tests.\n\n<b>Are there any chances of recovery for affected dogs?<\/b> A complete cure is not currently possible, but the symptoms can be well managed with medication and appropriate care protocols to improve the quality of life.\n\n<b>What treatment options are there?<\/b> Treatment usually involves administering medications that relieve the heart, as well as diuretics to reduce fluid accumulation. In some cases, surgery may also be considered. \n\n<b>Can the disease be prevented?<\/b>  There is no specific prevention measure, but a healthy lifestyle with a balanced diet and regular exercise can help reduce the risk.\n\n<b>What is the prognosis for dogs with this condition?<\/b>  The prognosis depends on the severity of the disease and the response to therapy. Many dogs can maintain a good quality of life with the right treatment. \n\n<b>How often should a dog with this condition be examined by a veterinarian?<\/b> Regular check-ups with the veterinarian are important to monitor the course of the disease and adjust treatment. Quarterly or semi-annual visits are often recommended. \n\n<b>Does the disease affect my dog's life expectancy?<\/b> Yes, the disease can affect life expectancy, especially if it is not diagnosed and treated in time. Early detection and treatment are crucial to maintaining quality of life. ","literaturangaben":"<ul>\n \t<li>Keene, B. W., Atkins, C. E., Bonagura, J. D., Fox, P. R., H\u00e4ggstr\u00f6m, J., Fuentes, V. L., Oyama, M. A., Rush, J. E., Stepien, R., & Uechi, M. (2019). ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs. Journal of Veterinary Internal Medicine, 33(3), 1127\u20131140.   https:\/\/doi.org\/10.1111\/jvim.15488<\/li>\n \t<li>Boswood, A., H\u00e4ggstr\u00f6m, J., Gordon, S. G., Wess, G., Stepien, R. L., Oyama, M. A., et al. (2016). Effect of pimobendan in dogs with preclinical myxomatous mitral valve disease and cardiomegaly: The EPIC study\u2014A randomized clinical trial. Journal of Veterinary Internal Medicine, 30(6), 1765\u20131779.  https:\/\/doi.org\/10.1111\/jvim.14586<\/li>\n \t<li>Chetboul, V., Tissier, R., Gouni, V., et al. (2012). Echocardiographic assessment of canine degenerative mitral valve disease. Journal of Veterinary Cardiology, 14(1), 127\u2013148.  https:\/\/doi.org\/10.1016\/j.jvc.2011.11.005<\/li>\n \t<li>Vezzosi, T., Domenech, O., Costa, G., et al. (2021). The mitral insufficiency echocardiographic score: A severity classification of myxomatous mitral valve disease in dogs. Journal of Veterinary Internal Medicine, 35(3), 1238\u20131244.  https:\/\/doi.org\/10.1111\/jvim.16131<\/li>\n \t<li>Svensson, M., Selling, J., & Dirven, M. (2024). Myxomatous mitral valve disease in large breed dogs: Survival characteristics and prognostic variables. Veterinary Sciences, 11(3), Article 136.   https:\/\/doi.org\/10.3390\/vetsci11030136<\/li>\n \t<li>Palarea-Albaladejo, J., Bode, E. F., Partington, C., Basili, M., Mederska, E., Hodgkiss-Geere, H., Capewell, P., Chauch\u00e9, C., Coultous, R. M., Hanks, E., & Dukes-McEwan, J. (2024). Effects of mitral valve repair on valvular geometry and hemodynamics in dogs with myxomatous mitral valve disease. Veterinary Surgery, 53(3), 415\u2013425.   https:\/\/doi.org\/10.1111\/vsu.14068<\/li>\n \t<li>Kurogochi, K., et al. (2025). Long-term outcomes of mitral valve repair with artificial chordae tendineae and annuloplasty in dogs with myxomatous mitral valve disease. Journal of Veterinary Internal Medicine, 39(4), 1912\u20131922.  https:\/\/doi.org\/10.1111\/jvim.17225<\/li>\n \t<li>Van Staveren, M. D. B., et al. (2024). Self-reported utilization of international (ACVIM consensus) guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs: A survey among veterinary practitioners. Animals, 14(5), Article 772.  https:\/\/doi.org\/10.3390\/ani14050772<\/li>\n \t<li>Keene, B. W., Atkins, C. E., Bonagura, J. D., Fox, P. R., H\u00e4ggstr\u00f6m, J., Fuentes, V. L., Oyama, M. A., Rush, J. E., Stepien, R., & Uechi, M. (2019). ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs. Journal of Veterinary Internal Medicine, 33(3), 1127\u20131140.   https:\/\/doi.org\/10.1111\/jvim.15488<\/li>\n \t<li>Boswood, A., H\u00e4ggstr\u00f6m, J., Gordon, S. G., Wess, G., Stepien, R. L., Oyama, M. A., et al. (2016). Effect of pimobendan in dogs with preclinical myxomatous mitral valve disease and cardiomegaly: The EPIC study\u2014A randomized clinical trial. Journal of Veterinary Internal Medicine, 30(6), 1765\u20131779.  https:\/\/doi.org\/10.1111\/jvim.14586<\/li>\n \t<li>Chetboul, V., Tissier, R., Gouni, V., et al. (2012). Echocardiographic assessment of canine degenerative mitral valve disease. Journal of Veterinary Cardiology, 14(1), 127\u2013148.  https:\/\/doi.org\/10.1016\/j.jvc.2011.11.005<\/li>\n \t<li>Vezzosi, T., Domenech, O., Costa, G., et al. (2021). The mitral insufficiency echocardiographic score: A severity classification of myxomatous mitral valve disease in dogs. Journal of Veterinary Internal Medicine, 35(3), 1238\u20131244.  https:\/\/doi.org\/10.1111\/jvim.16131<\/li>\n \t<li>Svensson, M., Selling, J., & Dirven, M. (2024). Myxomatous mitral valve disease in large breed dogs: Survival characteristics and prognostic variables. Veterinary Sciences, 11(3), Article 136.   https:\/\/doi.org\/10.3390\/vetsci11030136<\/li>\n \t<li>Palarea-Albaladejo, J., Bode, E. F., Partington, C., Basili, M., Mederska, E., Hodgkiss-Geere, H., Capewell, P., Chauch\u00e9, C., Coultous, R. M., Hanks, E., & Dukes-McEwan, J. (2024). Effects of mitral valve repair on valvular geometry and hemodynamics in dogs with myxomatous mitral valve disease. Veterinary Surgery, 53(3), 415\u2013425.   https:\/\/doi.org\/10.1111\/vsu.14068<\/li>\n \t<li>Kurogochi, K., et al. (2025). Long-term outcomes of mitral valve repair with artificial chordae tendineae and annuloplasty in dogs with myxomatous mitral valve disease. Journal of Veterinary Internal Medicine, 39(4), 1912\u20131922.  https:\/\/doi.org\/10.1111\/jvim.17225<\/li>\n \t<li>Van Staveren, M. D. B., et al. (2024). Self-reported utilization of international (ACVIM consensus) guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs: A survey among veterinary practitioners. Animals, 14(5), Article 772.  https:\/\/doi.org\/10.3390\/ani14050772<\/li>\n<\/ul>","symptome_ausgeblendet":"","erganzungen":"","faq":[{"frage":"1. What is Atrioventricular Valvular Endocardiosis?","antwort":"Atrioventricular valve endocardiosis is a chronic heart valve disease that is common in dogs. It leads to thickening and degeneration of the heart valves, which impairs heart function. "},{"frage":"2. What symptoms does a dog with this disease show?","antwort":"Common symptoms include Cough, shortness of breath, Lethargy, loss of appetite, and in advanced stages, fainting spells or sudden weakness."},{"frage":"3. Can all dog breeds be affected by this disease?","antwort":"Yes, in principle, all dog breeds can be affected, but small breeds such as Cavalier King Charles Spaniels, Poodles, and Dachshunds are more commonly affected."},{"frage":"4. How is the disease diagnosed?","antwort":"The diagnosis is usually made through a combination of physical examination, X-rays, cardiac ultrasound examinations, and blood tests."},{"frage":"5. Are there chances of recovery for affected dogs?","antwort":"A complete cure is currently not possible, but the symptoms can be well managed with medication and appropriate care protocols to improve quality of life."},{"frage":"6. What treatment options are available?","antwort":"Treatment usually involves administering medications that relieve the heart, as well as diuretic agents to reduce fluid accumulation. In some cases, surgical intervention may also be considered. "},{"frage":"7. Can the disease be prevented?","antwort":"There is no specific prevention measure, but a healthy lifestyle with a balanced diet and regular exercise can help reduce the risk."},{"frage":"8. What is the prognosis for dogs with this condition?","antwort":"The prognosis depends on the severity of the disease and the response to treatment. Many dogs can maintain a good quality of life with the right treatment. "},{"frage":"9. How often should a dog with this disease be examined by the veterinarian?","antwort":"Regular check-ups with the vet are important to monitor the course of the disease and adjust treatment. Quarterly or semi-annual visits are often recommended. "},{"frage":"10. Does the disease affect my dog's life expectancy?","antwort":"Yes, the disease can affect life expectancy, especially if it is not diagnosed and treated in time. Early detection and therapy are crucial to maintaining quality of life. 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