{"id":35992,"date":"2024-06-05T12:29:04","date_gmt":"2024-06-05T10:29:04","guid":{"rendered":"https:\/\/petsvetcheck.de\/krankheiten-und-stoerungen\/hund\/hyperparathyreoidismus-nebenschilddruesenueberfunktion\/"},"modified":"2026-08-14T04:35:01","modified_gmt":"2026-08-14T02:35:01","slug":"hyperparathyroidism-overactive-parathyroid-glands","status":"publish","type":"krankheit","link":"https:\/\/petsvetcheck.de\/en\/diseases-and-disorders\/dog\/hyperparathyroidism-overactive-parathyroid-glands\/","title":{"rendered":"Overactive Parathyroid Glands in Dogs (Hyperparathyroidism)"},"content":{"rendered":"","protected":false},"featured_media":0,"template":"","krankheitsort":[137],"haufigkeit":[136],"organsystem_krankheiten":[227],"class_list":["post-35992","krankheit","type-krankheit","status-publish","hentry","krankheitsort-bauch-becken-en","haufigkeit-b-en","organsystem_krankheiten-hormones-metabolism","entry"],"acf":{"synonyme":"","synonyme_en":"Overactive Parathyroid Glands","titel_en":"Hyperparathyroidism","weitere_suchbegriffe":"","triage":"yellow","triage_begruendung":"High calcium levels damage the kidneys and bones; treat the cause quickly.","definition":"Hyperparathyroidism in dogs is a condition in which the parathyroid glands produce too much parathyroid hormone (PTH), leading to elevated blood calcium levels.","ursachen":"The parathyroid glands are small glands located near the thyroid gland. They are essential for regulating blood calcium levels by producing parathyroid hormone (PTH). PTH raises blood calcium levels by promoting calcium absorption in the intestines, stimulating the release of calcium from bones, and reducing calcium excretion via the kidneys. Overproduction of PTH leads to hypercalcemia, a condition that can cause serious health problems in dogs. \n\nPrimary hyperparathyroidism is usually caused by an adenoma, a benign growth of the parathyroid glands. These tumors lead to uncontrolled production of PTH. More rarely, parathyroid carcinomas are the cause, which can also lead to overproduction of PTH. \n\nSecondary hyperparathyroidism can be caused by chronic kidney disease or by diet-related imbalances such as a calcium deficiency or an excess of phosphorus. In chronic kidney disease, the kidneys\u2019 ability to excrete phosphorus is impaired, leading to an imbalance of calcium and phosphorus and stimulating the parathyroid glands to produce more PTH. ","auswahl_symptome_rot":[10758,33938,34231,34056,34294],"auswahl_symptome_blau":[33618,33558,33810,34149,33201,34107],"auswahl_symptome_grun":[33550,33332,33493,33592,33553],"erganzungen_zu_symptomen":"Symptoms of hyperparathyroidism in dogs can be subtle and develop gradually. One of the most common symptoms is polyuria and polydipsia, meaning the dog urinates more than normal and is thirstier than usual. This happens due to the effect of elevated calcium on kidney function. \n\nOther signs may include loss of appetite, Vomiting, weakness, and Lethargy. Some dogs also show behavioral changes or seem depressed. In severe cases, Muscle weakness, tremors, and even bone pain can occur, as the body draws calcium from the bones to maintain the high blood level. \n\nOver the long term, hypercalcemia can lead to calcification of soft tissues and organs, especially the kidneys, impairing kidney function and ultimately leading to renal failure.","zusammenfassung":"Hyperparathyroidism in dogs is a condition in which the parathyroid glands produce too much parathyroid hormone (PTH), leading to elevated blood calcium levels. This can cause serious health problems. Primary hyperparathyroidism is often caused by a benign parathyroid adenoma, while secondary hyperparathyroidism can result from chronic kidney disease or diet-related imbalances. Symptoms include Lethargy, increased thirst and Urinary urgency, Weight loss, and Nausea. Diagnosis is made through clinical examinations, blood tests to check calcium and phosphorus levels, and imaging to detect Tumors. Treatment varies depending on the cause: primary hyperparathyroidism often requires surgical removal of the affected tissue, while secondary hyperparathyroidism involves treating the underlying condition. For acute hypercalcemia, fluid therapy may be necessary. The prognosis depends on the cause and stage of the disease, with early diagnosis and treatment improving the chances. There is no specific prevention for primary hyperparathyroidism, but regular veterinary check-ups can help detect problems early. For secondary hyperparathyroidism, a balanced diet is important. Research focuses on genetic predispositions, improved diagnostic methods, and new therapeutic approaches, including the role of diet and the microbiome in the course of the disease. ","diagnose":"Diagnosis of hyperparathyroidism usually begins with a thorough clinical examination and a detailed medical history. The veterinarian will ask whether there have been changes in drinking and urination habits and whether other symptoms such as Vomiting or loss of appetite have occurred. \n\nBlood tests are essential to check calcium levels. Elevated blood calcium is a strong indication of hyperparathyroidism. Phosphorus levels are also measured, as an imbalance between calcium and phosphorus can indicate problems with the parathyroid glands. \n\nA specific test to determine the PTH level in the blood can be performed to confirm the diagnosis. Imaging procedures such as ultrasound or X-rays can help identify tumors or abnormalities in the parathyroid glands. ","behandlung":"Treatment for hyperparathyroidism depends on the cause. In primary hyperparathyroidism caused by an adenoma, surgical removal of the affected tissue is the most common and effective therapy. This surgery requires careful postoperative monitoring of calcium levels, as they can drop suddenly after removal. \n\nIn secondary hyperparathyroidism caused by kidney disease, treatment focuses on the underlying condition. A special diet with reduced phosphorus and the use of phosphate binders can help restore the calcium\u2013phosphorus balance. \n\nIn acute cases of hypercalcemia, intravenous fluid therapy may be necessary to quickly lower calcium levels. Medications such as calcitonin or bisphosphonates may also be used to control calcium levels. ","prognose":"The prognosis for hyperparathyroidism depends on the cause and the stage of the disease. With timely diagnosis and treatment, the prognosis for dogs with primary hyperparathyroidism is usually good, especially if the adenoma can be successfully removed. \n\nIn secondary hyperparathyroidism caused by chronic kidney disease, the prognosis is more variable and depends on the progression of the kidney disease. Early intervention can slow progression and improve the dog\u2019s quality of life. ","ausblick_auf_aktuelle_forschung":"Current research on hyperparathyroidism in dogs focuses on understanding genetic predisposition and the molecular mechanisms that lead to this condition. Researchers are investigating how genetic markers in certain dog breeds could influence susceptibility to hyperparathyroidism. These studies aim to develop preventive measures and improve early diagnosis options through genetic testing. \n\nAnother important area of research is improving diagnostic methods. Scientists are working on developing non-invasive techniques to better assess parathyroid gland function. These techniques include advanced imaging methods such as high-resolution ultrasound and specialized blood tests that can detect specific hormonal changes. \n\nIn addition, research into therapeutic approaches is of great importance. New treatment strategies focus on developing medications that specifically target the overproduction of parathyroid hormone. This includes research into calcimimetics, which increase the parathyroid glands\u2019 sensitivity to calcium and could regulate hormone production. \n\nStudying the effects of environmental influences and diet on the development of hyperparathyroidism is another aspect of current research. Scientists are trying to understand how factors such as nutritional deficiencies\u2014especially related to calcium and vitamin D\u2014could increase the risk of the disease. These findings could lead to recommendations for dietary adjustments that reduce the risk of developing this condition. \n\nFinally, the role of the microbiome in relation to hyperparathyroidism is also being studied. Researchers are interested in how the intestinal flora \/ gut microbiota could influence calcium metabolism and parathyroid health. These insights could open up new perspectives for treatment and prevention by highlighting the importance of a healthy intestinal flora \/ gut microbiota for the dog\u2019s overall health. ","zusatzlicher_inhalt_im_hauptteil":"There is no specific prevention for primary hyperparathyroidism, as the development of parathyroid Tumors cannot be controlled. However, regular veterinary check-ups can help detect potential problems early. \n\nTo prevent secondary hyperparathyroidism, especially in dogs with kidney disease, a balanced diet is crucial. A diet with balanced calcium and phosphorus levels can help minimize the risk of imbalances. In dogs with known kidney problems, regular monitoring of kidney values and electrolyte balance is important. ","haufig_gestellte_fragen_faqs":"
    \n \t
  1. What is Hyperparathyroidism in Dogs?<\/b> Hyperparathyroidism is a condition in which the parathyroid glands produce too much parathyroid hormone (PTH). This hormone regulates calcium and phosphate metabolism in the body. Overproduction often leads to elevated blood calcium levels, which can cause various health problems. <\/li>\n \t
  2. What symptoms are typical of hyperparathyroidism in dogs?<\/b> The most common symptoms include increased thirst and frequent urination, loss of appetite, Vomiting, Lethargy, and weakness. In severe cases, bone pain or fractures may also occur. <\/li>\n \t
  3. What causes hyperparathyroidism in dogs?<\/b> The most common cause is a benign tumor of the parathyroid glands called an adenoma. Other causes may include genetic factors or rarer tumor types. Secondary hyperparathyroidism can be triggered by chronic kidney disease or nutritional problems. <\/li>\n \t
  4. How is hyperparathyroidism diagnosed in dogs?<\/b> Diagnosis is usually made through a combination of blood tests that measure calcium and parathyroid hormone levels, as well as imaging such as ultrasound to examine the parathyroid glands.<\/li>\n \t
  5. What treatment options are available for hyperparathyroidism in dogs?<\/b> Treatment depends on the cause. If there is a tumor, surgical removal of the affected parathyroid gland may be necessary. Medications can be used to regulate calcium levels. In some cases, dietary adjustments are required. <\/li>\n \t
  6. Can hyperparathyroidism be cured in dogs?<\/b> If the cause is a benign tumor and it is successfully removed, the dog can be completely cured. With other causes, or if the condition is linked to chronic kidney disease, long-term treatment may be necessary. <\/li>\n \t
  7. How can I reduce the risk of hyperparathyroidism in my dog?<\/b> A balanced diet with adequate calcium and vitamin D is important. Regular veterinary checkups can help detect the disease early. Genetic counseling can also be useful for certain breeds. <\/li>\n \t
  8. Which breeds are most commonly affected by hyperparathyroidism?<\/b> Certain breeds such as the Keeshond, Labrador Retriever, and German Shepherd show higher susceptibility. Genetic predisposition may play a role in these breeds. <\/li>\n \t
  9. Can a dog with hyperparathyroidism live a normal life?<\/b> With the right treatment and monitoring, many dogs can live a normal, healthy life. However, the prognosis depends on the severity of the disease and the underlying cause. <\/li>\n \t
  10. Are regular blood tests necessary for a dog with hyperparathyroidism?<\/b> Yes, regular blood tests are important to monitor calcium and parathyroid hormone levels and ensure that treatment is effective. These tests also help detect possible complications early. <\/li>\n<\/ol>","literaturangaben":"
      \n \t
    • Bonczynski, J. J. (2007). Primary hyperparathyroidism in dogs and cats. Clinical Techniques in Small Animal Practice, 22(2), 70\u201374. https:\/\/doi.org\/10.1053\/j.ctsap.2007.03.006<\/li>\n \t
    • Feldman, E. C., Hoar, B., Pollard, R., & Nelson, R. W. (2005). Pretreatment clinical and laboratory findings in dogs with primary hyperparathyroidism: 210 cases (1987\u20132004). Journal of the American Veterinary Medical Association, 227(5), 756\u2013761. https:\/\/doi.org\/10.2460\/javma.2005.227.756<\/li>\n \t
    • Gear, R. N. A., Neiger, R., Skelly, B. J., & Herrtage, M. E. (2005). Primary hyperparathyroidism in 29 dogs: diagnosis, treatment, outcome and associated renal failure. Journal of Small Animal Practice, 46(1), 10\u201316. https:\/\/doi.org\/10.1111\/j.1748-5827.2005.tb00274.x<\/li>\n \t
    • Rasor, L., Pollard, R., Feldman, E. C., & Nelson, R. W. (2007). Retrospective evaluation of three treatment methods for primary hyperparathyroidism in dogs. Journal of the American Animal Hospital Association, 43(2), 70\u201377. https:\/\/doi.org\/10.5326\/0430070<\/li>\n \t
    • Milovancev, M., Schmiedt, C. W., Radlinsky, M. G., Cornell, K. K., & Tillson, D. M. (2013). Preoperative factors associated with postoperative hypocalcemia in dogs with primary hyperparathyroidism that underwent parathyroidectomy: 62 cases (2004\u20132009). Journal of the American Veterinary Medical Association, 242(4), 507\u2013515. https:\/\/doi.org\/10.2460\/javma.242.4.507<\/li>\n \t
    • Guttin, T., Velayudhan, D. E., & Castellano, M. C. (2015). Outcomes for dogs with primary hyperparathyroidism following treatment with percutaneous ultrasound-guided ethanol ablation of functional parathyroid nodules: 24 cases (2008\u20132014). Journal of the American Veterinary Medical Association, 247(7), 771\u2013777. https:\/\/doi.org\/10.2460\/javma.247.7.771<\/li>\n \t
    • Burkhardt, S. J., Milovancev, M., & Schmiedt, C. W. (2021). Ambidirectional cohort study on the agreement of ultrasonography and surgery for parathyroid pathology in dogs with primary hyperparathyroidism. Veterinary Surgery, 50(8), 1627\u20131636. https:\/\/doi.org\/10.1111\/vsu.13707<\/li>\n \t
    • Young, K. M., Worley, D. R., & Ehrhart, N. P. (2023). Surgical description and outcome of ultrasound-guided minimally invasive parathyroidectomy in 45 dogs with primary hyperparathyroidism. Veterinary Surgery, 52(3), 426\u2013437. https:\/\/doi.org\/10.1111\/vsu.13924<\/li>\n<\/ul>","symptome_ausgeblendet":"","erganzungen":"","faq":[{"frage":"1. What is hyperparathyroidism in dogs?","antwort":"Hyperparathyroidism is a condition in which the parathyroid glands produce excessive amounts of parathyroid hormone (PTH). This hormone regulates calcium and phosphate metabolism in the body. Overproduction often leads to elevated calcium levels in the blood, which can cause various health problems."},{"frage":"2. Symptoms: What symptoms are typical of hyperparathyroidism in dogs?","antwort":"The most common symptoms include increased thirst and frequent urination, loss of appetite, vomiting, lethargy, and weakness. In severe cases, bone pain or fractures may also occur."},{"frage":"3. What causes hyperparathyroidism in dogs?","antwort":"The most common cause is a benign tumor of the parathyroid glands, called an adenoma. Other causes may include genetic factors or rarer tumor types. Secondary hyperparathyroidism can be triggered by chronic kidney disease or nutritional problems."},{"frage":"4. How is hyperparathyroidism in dogs diagnosed?","antwort":"Diagnosis is typically made through a combination of blood tests measuring calcium and parathyroid hormone levels, as well as imaging procedures such as ultrasound to examine the parathyroid glands."},{"frage":"5. What treatment options are available for hyperparathyroidism in dogs?","antwort":"Treatment depends on the cause. If a tumor is present, surgical removal of the affected parathyroid gland may be necessary. Medications can be used to regulate calcium levels. In some cases, dietary adjustments are required."},{"frage":"6. Can hyperparathyroidism in dogs be cured?","antwort":"If the cause is a benign tumor and it is successfully removed, the dog can be completely cured. For other causes or when the condition is associated with chronic kidney disease, long-term treatment may be necessary."},{"frage":"7. How can I reduce my dog\u2019s risk of hyperparathyroidism?","antwort":"A balanced diet with adequate calcium and vitamin D is important. Regular veterinary checkups can help detect the disease early. For certain breeds, genetic counseling may also be advisable."},{"frage":"8. Which breeds are most commonly affected by hyperparathyroidism?","antwort":"Certain breeds such as the Keeshond, Labrador Retriever, and German Shepherd show higher susceptibility. Genetic predisposition may play a role in these breeds."},{"frage":"9. Can a dog with hyperparathyroidism live a normal life?","antwort":"With proper treatment and monitoring, many dogs can lead normal and healthy lives. However, the prognosis depends on the severity of the condition and the underlying cause."},{"frage":"10. Are regular blood tests necessary for a dog with hyperparathyroidism?","antwort":"Yes, regular blood tests are important to monitor calcium and parathyroid hormone levels and ensure that treatment is effective. These tests also help detect potential complications early. 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