{"id":35824,"date":"2024-06-05T12:29:18","date_gmt":"2024-06-05T10:29:18","guid":{"rendered":"https:\/\/petsvetcheck.de\/krankheiten-und-stoerungen\/hund\/mesotheliom-tumoren-des-brustfells-des-bauchfells-und-anderer-weichteilgewebe\/"},"modified":"2026-08-10T18:20:09","modified_gmt":"2026-08-10T16:20:09","slug":"mesothelioma-tumors-of-the-pleura-peritoneum-and-other-soft-tissues","status":"publish","type":"krankheit","link":"https:\/\/petsvetcheck.de\/en\/diseases-and-disorders\/dog\/mesothelioma-tumors-of-the-pleura-peritoneum-and-other-soft-tissues\/","title":{"rendered":"Tumors of the pleura, peritoneum, and other soft tissues in dogs (Mesothelioma)"},"content":{"rendered":"","protected":false},"featured_media":0,"template":"","krankheitsort":[137,140],"haufigkeit":[135],"organsystem_krankheiten":[239,234],"class_list":["post-35824","krankheit","type-krankheit","status-publish","hentry","krankheitsort-bauch-becken-en","krankheitsort-brustkorb-en","haufigkeit-c-en","organsystem_krankheiten-general-full-body","organsystem_krankheiten-tumors","entry"],"acf":{"synonyme":"","synonyme_en":"Pleural Tumor; Peritoneal Tumor","titel_en":"Mesothelioma","weitere_suchbegriffe":"","triage":"yellow","triage_begruendung":"Pleural or peritoneal tumor with effusion; early diagnosis, relief, and oncology planning.","definition":"Mesothelioma is a rare, malignant tumor that occurs in dogs, primarily affecting the pleura, peritoneum, or other soft tissues.\n\nBASICS\/CAUSES:\n\nMesotheliomas arise from mesothelial cells that line the serous cavities of the body, such as the pleura and peritoneum. These cells provide a protective, lubricating surface that facilitates organ movement. Mesothelioma is an aggressive tumor form characterized by uncontrolled cell growth in these tissues.  \n\nThe exact causes for the occurrence of mesotheliomas in dogs are not yet fully understood. However, there are indications that environmental factors could play a role. In humans, asbestos exposure is a known cause of mesotheliomas, and similar connections have been suspected in dogs.  \n\nGenetic factors could also play a role by influencing the susceptibility to the development of Tumors. An accumulation of mesothelioma cases has been observed in certain dog breeds, which could indicate a genetic predisposition. \n\nAnother possible trigger is chronic Inflammatory conditions in the chest or abdominal cavity, which could increase the risk of mesothelioma development. These Inflammatory conditions could be caused by repeated injuries or infections. ","ursachen":"<ul>\n \t<li>The exact cause of mesotheliomas is not well understood in dogs. In humans, an association with asbestos exposure is discussed, but for dogs, this is less clearly defined. <\/li>\n<\/ul>","auswahl_symptome_rot":[33807,33809,33803,34191,33816],"auswahl_symptome_blau":[34024,33880,33332,33810,34231,34183,33423],"auswahl_symptome_grun":[33743,33190,34260,34183],"erganzungen_zu_symptomen":"The symptoms of mesothelioma in dogs can vary depending on which tissue is affected. However, general symptoms are often nonspecific and pose a challenge in diagnosis. \n\nIn mesothelioma of the pleura, Respiratory distress, Cough, or reduced exercise tolerance may occur, as fluid can accumulate in the chest cavity, known as pleural effusion.\n\nMesothelioma of the peritoneum can lead to symptoms such as Abdominal pain, Vomiting, Diarrhea, or a bloated abdomen. Here too, fluid can accumulate, which is known as ascites. \n\nIn advanced stages, Weight loss, loss of appetite, and general weakness may occur. These symptoms are often the result of the metabolic burden from the tumor and associated complications. ","zusammenfassung":"Mesotheliomas in dogs are Tumors that affect the pleura or peritoneum. The exact cause is not well understood, but unlike in humans, there is no clear connection with asbestos. Symptoms can include reduced exercise tolerance, Abdominal pain, loss of appetite, and respiratory problems. Occasionally, Respiratory distress or fluid accumulations in the abdominal cavity occur. Diagnosis is made through clinical examinations and imaging such as X-ray or ultrasound; often a biopsy is necessary to confirm the diagnosis. Treatment requires a multimodal approach that may include surgery, radiation therapy, and chemotherapy, with the focus on alleviating symptoms and improving quality of life. Early diagnosis can improve the prognosis, but survival time is often limited. Since the causes are unclear, specific prevention strategies are lacking, although minimizing exposure to carcinogenic substances is recommended. Research focuses on developing better diagnostic methods and new therapies, such as immunotherapy. Advances in imaging and the identification of biomarkers could improve early detection. An interdisciplinary approach is crucial to improving the quality of life of affected dogs and developing new treatment options.          ","diagnose":"The diagnosis of mesothelioma in dogs requires a careful clinical examination as well as the use of diagnostic imaging techniques. X-rays and ultrasound examinations are often the first steps in identifying fluid accumulations or tumorous changes. \n\nComputed tomography (CT) or magnetic resonance imaging (MRI) can provide more detailed information about the extent of the tumor. These procedures are helpful in determining the exact extent of the disease and planning treatment. \n\nA definitive diagnosis usually requires a biopsy, in which a tissue sample of the tumor is taken and examined microscopically. This examination can confirm whether it is a mesothelioma and which cell type is involved. \n\nAdditionally, cytological examinations of fluid from pleural effusions or ascites can be performed to find evidence of malignant cells. However, these analyses are often less specific than a biopsy. ","behandlung":"The treatment of mesotheliomas in dogs is complex and often requires a multimodal approach. Surgical interventions may be considered to remove the tumor or alleviate symptoms, especially if the tumor is localized. \n\nRadiation therapy can be used in some cases to reduce tumor mass and alleviate symptoms. However, effectiveness depends on the location and extent of the tumor. \n\nChemotherapy can also be an option, either as a standalone treatment or in combination with surgery and radiation therapy. Some chemotherapeutic agents can slow tumor growth but must be carefully monitored for side effects. \n\nPalliative care, which focuses on alleviating symptoms and improving quality of life, is often an important component of the treatment plan. This includes the treatment of pleural effusions or ascites as well as the prescription of pain medications. ","prognose":"The prognosis for dogs with mesothelioma is generally guarded to poor, as it is an aggressive tumor type that is often detected late. Survival time depends on many factors, including tumor location, extent at diagnosis, and the chosen treatment. \n\nDogs that are diagnosed early and treated comprehensively may have a better prognosis, but median survival time is often only a few months. Regular follow-up examinations are important to monitor disease progression and adjust treatment accordingly. ","ausblick_auf_aktuelle_forschung":"Research on mesotheliomas in dogs has gained importance in recent years, as this tumor type is relatively rare and difficult to diagnose. Veterinarians and researchers are focusing on better understanding the causes and developing more effective diagnostic methods. It is believed that environmental factors, genetic predispositions, and possibly asbestos exposure could play a role, similar to humans. However, the connection in dogs is less clear, as they are less frequently in direct contact with asbestos.   \n\nSome studies have focused on identifying biomarkers that could enable early detection of mesotheliomas. These biomarkers could be detected in blood or other body fluids and help diagnose the disease at an earlier stage, which could improve treatment options. The development of imaging procedures specifically aimed at detecting mesotheliomas is also an active research area. Advances in imaging could help increase the accuracy and speed of diagnosis.   \n\nRegarding treatment, scientists are researching new drug-based and targeted therapies that target the molecular properties of mesotheliomas. Another promising direction is immunotherapy, which aims to strengthen the dog's immune system to fight tumor cells more effectively. Clinical trials are underway to evaluate the efficacy and safety of such therapies.  \n\nAn interdisciplinary approach that combines veterinary medicine, molecular biology, and oncology is considered crucial to achieving progress in combating mesotheliomas in dogs. Collaborations between universities, research institutions, and veterinary hospitals help deepen the understanding of this complex disease and develop innovative treatment approaches. \n\nIn summary, research on mesotheliomas in dogs is continuously advancing, but many questions remain open. Ongoing efforts aim to improve the quality of life and survival rates of affected dogs while gaining new insights that may also be significant for understanding the disease in humans. ","zusatzlicher_inhalt_im_hauptteil":"Since the exact causes of mesotheliomas in dogs are not fully understood, there are currently no specific prevention strategies. Minimizing exposure to known carcinogenic substances such as asbestos could reduce the risk, however. \n\nRegular veterinary examinations can help detect health changes early, which increases the chances of timely diagnosis and treatment.\n\nA healthy lifestyle, including a balanced diet and adequate exercise, can contribute to the overall health of the dog and potentially reduce the risk of various diseases, including Tumors.","haufig_gestellte_fragen_faqs":"<ol>\n \t<li><b>What is a mesothelioma in dogs?<\/b> A mesothelioma is a rare tumor that affects the mesothelium, a thin layer of tissue that lines the internal organs. In dogs, these Tumors occur primarily on the pleura or peritoneum. <\/li>\n \t<li><b>What symptoms do dogs with mesotheliomas show?<\/b> Symptoms can vary but often include Respiratory distress, Cough, lethargy, Weight loss, and fluid accumulations in the chest or abdominal cavity.<\/li>\n \t<li><b>How is a mesothelioma diagnosed in dogs?<\/b>  Diagnosis is usually made through a combination of clinical examinations, imaging procedures such as X-ray or ultrasound, and the analysis of tissue samples (biopsy).<\/li>\n \t<li><b>What are the causes of mesotheliomas in dogs?<\/b> The exact causes are unclear, but it is suspected that genetic factors, environmental factors, and possibly exposure to asbestos could play a role.<\/li>\n \t<li><b>Can mesotheliomas be treated in dogs?<\/b> Yes, there are various treatment options, including surgery, chemotherapy, and in some cases radiation therapy. The choice of treatment depends on the stage and location of the tumor. <\/li>\n \t<li><b>What are the survival chances for dogs with mesotheliomas?<\/b> The prognosis is often guarded, as mesotheliomas can be aggressive. Early diagnosis and treatment can improve survival chances. <\/li>\n \t<li><b>Are there preventive measures to avoid mesotheliomas in dogs?<\/b>  Since the exact causes are unknown, there are no specific preventive measures. However, a healthy lifestyle and regular veterinary examinations can be helpful. <\/li>\n \t<li><b>Are certain dog breeds more susceptible to mesotheliomas?<\/b>  So far, there is no clear evidence that certain breeds are more susceptible. However, genetic factors could play a role in the development. <\/li>\n \t<li><b>Can mesotheliomas in dogs be contagious?<\/b> No, mesotheliomas are not contagious. It is a tumor caused by internal factors. <\/li>\n \t<li><b>What research is being conducted on mesotheliomas in dogs?<\/b>  Research includes the search for biomarkers, the development of new diagnosis methods and treatments, and the understanding of the genetic and molecular basis of the disease.<\/li>\n<\/ol>","literaturangaben":"<ul>\n \t<li>Moberg, H. L., Gramer, I., Schofield, I., Guill\u00e9n, A., et al. (2022). Clinical presentation, treatment and outcome of canine malignant mesothelioma: A retrospective study of 34 cases. Veterinary and Comparative Oncology, 20(1), 304\u2013312.  https:\/\/doi.org\/10.1111\/vco.12777<\/li>\n \t<li>Lajoinie, M., Chavalle, T., Floch, F., Sayag, D., Lanore, D., Ponce, F., & Chamel, G. (2022). Outcome of dogs treated with chemotherapy for mesothelioma: A retrospective clinical study on 40 cases and a literature review. Veterinary and Comparative Oncology, 20(4), 825\u2013835.   https:\/\/doi.org\/10.1111\/vco.12843<\/li>\n \t<li>Milne, E., Martinez-Pereira, Y., Muir, C., Scase, T., Shaw, D., McGregor, G., Oldroyd, L., Scurrell, E., Martin, M., Devine, C., & Hodgkiss-Geere, H. (2018). Immunohistochemical differentiation of reactive from malignant mesothelium as a diagnostic aid in canine pericardial disease. Journal of Small Animal Practice, 59(5), 261\u2013271.   https:\/\/doi.org\/10.1111\/jsap.12830<\/li>\n \t<li>Milne, E. M., Piviani, M., Hodgkiss-Geere, H. M., Piccinelli, C., Cheeseman, M., Cazzini, P., Ressel, L., Marcos, R. J., Marrinhas, C. S., Santos, M. S., Thomas, E., Drummond, D., & Martinez Pereira, Y. (2021). Comparison of effusion cell block and biopsy immunohistochemistry in mesothelial hyperplasia, mesothelioma, and carcinoma in dogs. Veterinary Clinical Pathology, 50(1).   https:\/\/doi.org\/10.1111\/vcp.13002<\/li>\n \t<li>Nabeta, R., et al. (2024). Characterization of mesothelin gene expression in dogs and evaluation as a diagnostic biomarker for canine mesothelioma. Frontiers in Veterinary Science, 11, Article 1436621. https:\/\/doi.org\/10.3389\/fvets.2024.1436621<\/li>\n \t<li>Harbison, M. L., & Godleski, J. J. (1983). Malignant mesothelioma in urban dogs. Veterinary Pathology, 20(5), 531\u2013540.   https:\/\/doi.org\/10.1177\/030098588302000504<\/li>\n \t<li>D'Angelo, A. R., Di Francesco, G., De Vico, G., & Staiano, N. (2014). Sclerosing peritoneal mesothelioma in a dog: Histopathological, histochemical and immunohistochemical investigations. Veterinaria Italiana, 50(4), 301\u2013305.   https:\/\/doi.org\/10.12834\/VetIt.20.1309.130<\/li>\n<\/ul>","symptome_ausgeblendet":"","erganzungen":"","faq":[{"frage":"1. What is a mesothelioma in dogs?","antwort":"Mesothelioma is a rare tumor that affects the mesothelium, a thin layer of tissue that lines the internal organs. In dogs, these Tumors mainly occur in the lining of the chest or abdomen. -"},{"frage":"2. What symptoms do dogs with mesotheliomas show?","antwort":"Symptoms can vary but often include Respiratory distress, Cough, lethargy, Weight loss, and fluid accumulation in the chest or abdominal cavity. -"},{"frage":"3. How is a mesothelioma diagnosed in dogs?","antwort":"The diagnosis is usually made through a combination of clinical examinations, imaging techniques such as X-ray or ultrasound, and the analysis of tissue samples (biopsy). -"},{"frage":"4. What are the causes of mesotheliomas in dogs?","antwort":"The exact causes are unclear, but it is believed that genetic factors, environmental factors, and possibly exposure to asbestos could play a role. -"},{"frage":"5. Can mesotheliomas be treated in dogs?","antwort":"Yes, there are various treatment options, including surgery, chemotherapy, and in some cases, radiation therapy. The choice of treatment depends on the stage and location of the tumor. -"},{"frage":"6. What are the survival chances for dogs with mesotheliomas?","antwort":"The prognosis is often guarded, as mesotheliomas can be aggressive. Early diagnosis and treatment can improve the chances of survival. -"},{"frage":"7. Are there preventive measures to avoid mesotheliomas in dogs?","antwort":"Since the exact causes are unknown, there are no specific preventive measures. However, a healthy lifestyle and regular veterinary check-ups can be helpful. -"},{"frage":"8. Are certain dog breeds more susceptible to mesotheliomas?","antwort":"So far, there is no clear evidence that certain breeds are more susceptible. However, genetic factors could play a role in its development. -"},{"frage":"9. Can mesotheliomas in dogs be contagious?","antwort":"No, mesotheliomas are not contagious. It is a tumor that develops due to internal factors. -"},{"frage":"10. What research is being conducted on mesotheliomas in dogs?","antwort":"Research includes the search for biomarkers, the development of new diagnostic methods and treatments, and understanding the genetic and molecular basis of the disease."}],"faq_html":null},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.5 (Yoast SEO v28.5) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Tumors of the pleura, peritoneum, and other soft tissues in dogs (Mesothelioma) in dogs<\/title>\n<meta name=\"description\" content=\"Learn more about mesotheliomas (Tumors of serous membranes in body cavities and organ coverings) and their impact on canine health.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/petsvetcheck.de\/en\/diseases-and-disorders\/dog\/mesothelioma-tumors-of-the-pleura-peritoneum-and-other-soft-tissues\/\" \/>\n<meta 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